Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ABC814_RS09720 Genome accession   NZ_CP155533
Coordinates   1877244..1878500 (-) Length   418 a.a.
NCBI ID   WP_083973677.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Spn1439-106     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1872244..1883500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC814_RS09695 (ABC814_09695) - 1872301..1872507 (-) 207 WP_000366087.1 hypothetical protein -
  ABC814_RS09700 (ABC814_09700) - 1872494..1872655 (-) 162 WP_000289348.1 helix-turn-helix transcriptional regulator -
  ABC814_RS09705 (ABC814_09705) lytA 1873014..1873970 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  ABC814_RS09710 (ABC814_09710) - 1874346..1875716 (-) 1371 WP_001036282.1 MATE family efflux transporter -
  ABC814_RS09715 (ABC814_09715) recA 1876023..1877189 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  ABC814_RS09720 (ABC814_09720) cinA 1877244..1878500 (-) 1257 WP_083973677.1 competence/damage-inducible protein A Machinery gene
  ABC814_RS09725 (ABC814_09725) - 1878585..1879601 (-) 1017 WP_000239282.1 LCP family protein -
  ABC814_RS09730 (ABC814_09730) - 1879609..1880127 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  ABC814_RS09735 (ABC814_09735) tsaE 1880117..1880560 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ABC814_RS09740 (ABC814_09740) comM 1880647..1881267 (-) 621 WP_000839908.1 hypothetical protein Regulator
  ABC814_RS09745 (ABC814_09745) - 1881650..1882513 (-) 864 WP_001093623.1 helix-turn-helix transcriptional regulator -
  ABC814_RS09750 (ABC814_09750) - 1882702..1882872 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45046.49 Da        Isoelectric Point: 4.7019

>NTDB_id=997191 ABC814_RS09720 WP_083973677.1 1877244..1878500(-) (cinA) [Streptococcus pneumoniae strain Spn1439-106]
MKAEIIAVGTEILTGQIVNTNAQFLSKKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=997191 ABC814_RS09720 WP_083973677.1 1877244..1878500(-) (cinA) [Streptococcus pneumoniae strain Spn1439-106]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGAA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.043

100

0.99
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

94.019

100

0.94
  cinA Streptococcus mitis NCTC 12261

93.78

100

0.938
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

100

0.459

Multiple sequence alignment