Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NSQ96_RS08375 Genome accession   NZ_CP155465
Coordinates   1723219..1724454 (+) Length   411 a.a.
NCBI ID   WP_346200869.1    Uniprot ID   -
Organism   Caldifermentibacillus hisashii strain FSL K6-2851     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1720552..1745248 1723219..1724454 within 0


Gene organization within MGE regions


Location: 1720552..1745248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NSQ96_RS08360 (NSQ96_08360) - 1720744..1721535 (+) 792 WP_041846659.1 DUF3388 domain-containing protein -
  NSQ96_RS08365 (NSQ96_08365) - 1721553..1722449 (+) 897 WP_342020118.1 RodZ domain-containing protein -
  NSQ96_RS08370 (NSQ96_08370) pgsA 1722567..1723145 (+) 579 WP_346200868.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NSQ96_RS08375 (NSQ96_08375) cinA 1723219..1724454 (+) 1236 WP_346200869.1 competence/damage-inducible protein A Machinery gene
  NSQ96_RS08380 (NSQ96_08380) - 1724360..1726282 (-) 1923 WP_346200870.1 IS1182 family transposase -
  NSQ96_RS08385 (NSQ96_08385) - 1726518..1726766 (+) 249 WP_034769901.1 hypothetical protein -
  NSQ96_RS08390 (NSQ96_08390) - 1726814..1727164 (+) 351 WP_034769902.1 hypothetical protein -
  NSQ96_RS08395 (NSQ96_08395) - 1727302..1727748 (+) 447 WP_034769958.1 YaiI/YqxD family protein -
  NSQ96_RS08400 (NSQ96_08400) - 1727831..1727968 (+) 138 WP_346200871.1 hypothetical protein -
  NSQ96_RS08405 (NSQ96_08405) - 1727935..1728072 (+) 138 WP_216408306.1 hypothetical protein -
  NSQ96_RS08410 (NSQ96_08410) - 1728143..1728280 (+) 138 WP_346200872.1 hypothetical protein -
  NSQ96_RS08415 (NSQ96_08415) - 1728299..1728436 (+) 138 WP_346200871.1 hypothetical protein -
  NSQ96_RS08420 (NSQ96_08420) - 1728455..1728592 (+) 138 WP_343156914.1 hypothetical protein -
  NSQ96_RS08425 (NSQ96_08425) - 1728611..1728799 (+) 189 WP_346200873.1 hypothetical protein -
  NSQ96_RS08430 (NSQ96_08430) - 1728977..1729891 (-) 915 WP_231553313.1 CAP domain-containing protein -
  NSQ96_RS08435 (NSQ96_08435) - 1730363..1730464 (+) 102 WP_268756472.1 putative holin-like toxin -
  NSQ96_RS08440 (NSQ96_08440) - 1730910..1731080 (+) 171 WP_231553317.1 metal-sensing transcriptional repressor -
  NSQ96_RS08445 (NSQ96_08445) - 1731140..1731649 (+) 510 Protein_1632 glycogen/starch/alpha-glucan phosphorylase -
  NSQ96_RS08450 (NSQ96_08450) - 1731842..1732102 (+) 261 WP_034769908.1 transcriptional regulator SplA domain-containing protein -
  NSQ96_RS08455 (NSQ96_08455) splB 1732120..1733148 (+) 1029 WP_041846657.1 spore photoproduct lyase -
  NSQ96_RS08460 (NSQ96_08460) - 1733281..1733547 (+) 267 WP_034769963.1 YqhV family protein -
  NSQ96_RS08465 (NSQ96_08465) - 1733613..1734368 (-) 756 WP_251240945.1 acyl-ACP thioesterase domain-containing protein -
  NSQ96_RS08470 (NSQ96_08470) - 1734587..1734844 (-) 258 WP_041846797.1 DUF5348 domain-containing protein -
  NSQ96_RS08475 (NSQ96_08475) - 1734841..1735641 (-) 801 WP_346199918.1 AAA family ATPase -
  NSQ96_RS08480 (NSQ96_08480) - 1735634..1736902 (-) 1269 WP_346199919.1 IS481 family transposase -
  NSQ96_RS08485 (NSQ96_08485) - 1737039..1737569 (-) 531 WP_108897264.1 DUF6431 domain-containing protein -
  NSQ96_RS08490 (NSQ96_08490) - 1737824..1738150 (+) 327 WP_095141875.1 metalloregulator ArsR/SmtB family transcription factor -
  NSQ96_RS08495 (NSQ96_08495) - 1738310..1739254 (+) 945 WP_034769912.1 cation diffusion facilitator family transporter -
  NSQ96_RS08500 (NSQ96_08500) - 1739351..1739479 (-) 129 WP_255602025.1 hypothetical protein -
  NSQ96_RS08505 (NSQ96_08505) - 1739538..1739972 (-) 435 WP_251240944.1 NAD(P)H-dependent oxidoreductase -
  NSQ96_RS08510 (NSQ96_08510) - 1740030..1740209 (+) 180 Protein_1645 vitamin B12 dependent-methionine synthase activation domain-containing protein -
  NSQ96_RS08515 (NSQ96_08515) - 1740446..1741378 (+) 933 WP_251240943.1 aldo/keto reductase -
  NSQ96_RS08520 (NSQ96_08520) ilvD 1741699..1743369 (-) 1671 WP_041846656.1 dihydroxy-acid dehydratase -
  NSQ96_RS08525 (NSQ96_08525) - 1743917..1744714 (+) 798 WP_251240942.1 HAD family hydrolase -
  NSQ96_RS08530 (NSQ96_08530) - 1744806..1744985 (+) 180 WP_251240941.1 hypothetical protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 45301.86 Da        Isoelectric Point: 5.0277

>NTDB_id=996529 NSQ96_RS08375 WP_346200869.1 1723219..1724454(+) (cinA) [Caldifermentibacillus hisashii strain FSL K6-2851]
MNGEIIAVGSELLLGQIANTNAKFISQQLAGIGVNVFYHTVVGDNAERLRRAVEIAESRSNLIIFTGGLGPTKDDLTKET
IANHLGVKLIHNEAALVSIEEFFRKRNVTMTPNNRKQALVFEHAEVLPNDTGMAPGMVLTKNEITYMLLPGPPSEMEPMF
SNYGMKAILNRLESIDRIESRVLRFFGIGESTLEHTLEDFIDQQTNPTIAPLASDGEVTLRLTAKHPSDLERRRLLDETE
AKIMERVGEFFYGYDETTIIKEMGNLIESKNMTLSVAESLTGGLFQEEVTSIAGVSKWFQGGIVSYSPEIKINVLGVNPD
TVETYGVVSKECAMEMAENVRKLMDTDIGISFTGVAGPASLEGKEPGSVYIGVSFKNKPTASHFVLLPGNRETVRVRAVK
TGAWYILKELR

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=996529 NSQ96_RS08375 WP_346200869.1 1723219..1724454(+) (cinA) [Caldifermentibacillus hisashii strain FSL K6-2851]
TTGAATGGTGAAATTATTGCCGTTGGGTCTGAATTATTACTTGGCCAAATTGCTAATACGAATGCAAAATTTATTTCTCA
ACAATTGGCCGGTATTGGGGTAAATGTATTTTACCATACCGTTGTTGGGGATAATGCCGAGCGGTTGAGAAGAGCGGTGG
AAATTGCCGAAAGTCGTTCCAATTTAATTATATTTACGGGTGGCTTAGGGCCTACAAAAGATGATTTAACAAAAGAAACC
ATTGCAAATCATCTGGGAGTGAAGCTCATTCATAATGAAGCGGCTCTTGTCTCGATAGAAGAATTTTTTAGAAAACGGAA
TGTTACCATGACACCGAATAATCGGAAACAAGCACTTGTTTTTGAACATGCGGAGGTTTTGCCAAACGATACCGGAATGG
CACCGGGAATGGTGTTAACAAAAAATGAAATTACTTATATGCTACTTCCCGGTCCGCCTAGTGAAATGGAGCCGATGTTT
TCAAATTATGGGATGAAAGCAATCCTAAATCGGTTGGAATCCATTGATCGAATTGAATCTCGTGTGTTACGATTTTTTGG
TATTGGTGAATCAACTCTGGAACATACGCTGGAAGATTTCATTGATCAGCAGACAAACCCGACCATTGCCCCGCTCGCTT
CTGATGGCGAAGTGACATTGCGGCTTACAGCTAAACATCCCTCAGATCTTGAACGAAGAAGGTTACTGGATGAGACAGAA
GCAAAAATTATGGAGCGGGTGGGTGAATTTTTTTACGGATATGATGAAACAACAATTATCAAAGAAATGGGCAATTTGAT
TGAAAGCAAGAACATGACACTTTCGGTAGCTGAAAGTTTAACGGGCGGACTGTTTCAGGAAGAAGTGACATCCATTGCCG
GTGTCAGCAAATGGTTTCAGGGCGGGATCGTATCGTATTCCCCTGAAATAAAAATAAATGTACTTGGCGTAAATCCGGAC
ACTGTTGAAACTTATGGTGTCGTCAGTAAAGAATGCGCAATGGAGATGGCAGAAAATGTCCGAAAATTGATGGACACTGA
TATCGGAATCAGCTTTACCGGTGTTGCCGGACCAGCCTCATTGGAAGGAAAAGAACCCGGTTCAGTTTATATTGGTGTGT
CATTTAAGAATAAGCCTACCGCTAGTCATTTTGTCTTATTGCCGGGAAACAGAGAAACGGTTCGTGTCCGTGCCGTAAAA
ACCGGTGCATGGTATATATTAAAGGAACTTCGGTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-165)

Competence-damaged protein (CinA)

(258-404)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

61.179

99.027

0.606
  cinA Streptococcus mutans UA159

45.926

98.54

0.453
  cinA Streptococcus pneumoniae TIGR4

47.781

93.187

0.445
  cinA Streptococcus mitis NCTC 12261

47.52

93.187

0.443
  cinA Streptococcus mitis SK321

47.52

93.187

0.443
  cinA Streptococcus pneumoniae Rx1

47.52

93.187

0.443
  cinA Streptococcus pneumoniae R6

47.52

93.187

0.443
  cinA Streptococcus pneumoniae D39

47.258

93.187

0.44
  cinA Streptococcus suis isolate S10

39.578

92.214

0.365

Multiple sequence alignment