Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MKY25_RS11540 Genome accession   NZ_CP151952
Coordinates   2327600..2328844 (-) Length   414 a.a.
NCBI ID   WP_033023150.1    Uniprot ID   A0A150MH17
Organism   Geobacillus sp. FSL W8-0032     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 2322600..2333844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKY25_RS11520 (MKY25_11520) spoVS 2323059..2323319 (-) 261 WP_003251598.1 stage V sporulation protein SpoVS -
  MKY25_RS11525 (MKY25_11525) - 2323450..2324244 (-) 795 WP_033023154.1 TIGR00282 family metallophosphoesterase -
  MKY25_RS11530 (MKY25_11530) rny 2324343..2325899 (-) 1557 WP_033023152.1 ribonuclease Y -
  MKY25_RS11535 (MKY25_11535) recA 2326376..2327419 (-) 1044 WP_033023151.1 recombinase RecA Machinery gene
  MKY25_RS11540 (MKY25_11540) cinA 2327600..2328844 (-) 1245 WP_033023150.1 competence/damage-inducible protein A Machinery gene
  MKY25_RS11545 (MKY25_11545) pgsA 2328875..2329453 (-) 579 WP_033023148.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MKY25_RS11550 (MKY25_11550) - 2329528..2330409 (-) 882 WP_033023146.1 helix-turn-helix domain-containing protein -
  MKY25_RS11555 (MKY25_11555) - 2330616..2331407 (-) 792 WP_033023144.1 DUF3388 domain-containing protein -
  MKY25_RS11560 (MKY25_11560) - 2331659..2331913 (-) 255 WP_033023142.1 DUF3243 domain-containing protein -
  MKY25_RS11565 (MKY25_11565) - 2332448..2333164 (-) 717 WP_033023141.1 SDR family oxidoreductase -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 44380.11 Da        Isoelectric Point: 7.1722

>NTDB_id=981915 MKY25_RS11540 WP_033023150.1 2327600..2328844(-) (cinA) [Geobacillus sp. FSL W8-0032]
MNAEIIAVGSELLLGQIVNTNAQFLSQQLAALGINVYFQTVVGDNAGRLEQAVKTAQTRANLIIFTGGLGPTKDDVTKET
IARLLGRRLVIDEEALRAIEAYFARAHRPMTDNNKKQALVLEGATVLKNENGMAPGMALTVAGITYMLLPGPPKEMRPMF
TRYGIPFLRAAFPLSGRIESRVLRFFGIGEAALETALADLIDAQSNPTIAPLAGDGEVTLRLTAKHRDAAEAQRLLDEAE
AAILARVGRYCYGYDDETLFTKTSERLKERGWTIAAAESLTGGLFLEQLTAVPGASRIVQGGVVCYTNGVKQQVLGVPRP
LLETDGAVSESCARVLAENVRSLCGADVGISFTGVAGPDPLEGHPPGTVYIGIAMRERGTAVRRLTLSGTRGDIRIRAAK
YGCFLLLELLAADR

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=981915 MKY25_RS11540 WP_033023150.1 2327600..2328844(-) (cinA) [Geobacillus sp. FSL W8-0032]
TTGAACGCGGAGATCATCGCCGTCGGCTCGGAACTGCTGCTTGGCCAAATTGTCAACACGAACGCCCAGTTTTTGTCGCA
GCAGCTTGCCGCCTTGGGCATCAATGTTTATTTCCAGACGGTTGTCGGCGACAACGCCGGCCGCCTTGAGCAGGCGGTGA
AAACGGCGCAAACGAGGGCGAATCTCATCATCTTCACCGGCGGTCTCGGCCCGACGAAGGATGATGTCACGAAGGAGACG
ATCGCCCGTTTGCTTGGCCGCCGGCTCGTCATCGATGAAGAGGCGTTGCGGGCAATCGAAGCGTACTTTGCCCGCGCCCA
TCGGCCGATGACAGACAACAACAAAAAGCAAGCGCTCGTTTTGGAAGGGGCGACCGTCCTGAAAAACGAAAACGGCATGG
CGCCGGGGATGGCGCTCACCGTCGCGGGCATCACGTACATGTTGCTGCCCGGGCCGCCGAAAGAAATGCGCCCGATGTTT
ACCCGTTACGGGATCCCCTTTTTGCGCGCTGCGTTCCCGCTGTCCGGACGCATTGAGTCGCGTGTGCTCCGCTTTTTTGG
CATCGGCGAAGCGGCGCTGGAGACGGCGCTCGCCGATTTGATTGACGCGCAATCGAATCCGACGATCGCGCCGCTGGCCG
GTGACGGCGAGGTGACGCTCCGCTTGACGGCGAAGCACCGGGACGCGGCGGAAGCGCAGCGGCTGCTTGATGAAGCAGAA
GCGGCGATTTTGGCGCGCGTTGGCCGCTACTGTTACGGCTATGACGACGAAACGCTGTTTACGAAGACAAGCGAACGGTT
AAAAGAAAGAGGATGGACGATCGCGGCGGCCGAGAGCCTGACCGGCGGGCTGTTTCTCGAACAGCTCACCGCCGTTCCCG
GGGCGTCGCGGATCGTTCAAGGCGGCGTCGTTTGCTACACGAACGGCGTCAAACAACAGGTGCTTGGCGTGCCGCGGCCG
CTTCTCGAAACGGACGGGGCGGTGAGCGAATCGTGCGCGCGTGTGTTGGCGGAAAACGTCCGTTCGCTATGCGGCGCCGA
TGTCGGCATCAGCTTCACCGGCGTCGCCGGCCCCGACCCGCTTGAAGGCCATCCGCCCGGCACCGTCTATATCGGCATTG
CCATGCGCGAGCGCGGCACCGCTGTCCGCCGTTTGACGTTGTCCGGCACGCGCGGCGACATCCGCATCCGCGCCGCCAAA
TACGGTTGTTTTCTGCTGCTGGAGCTGCTTGCGGCCGACCGCTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A150MH17

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

59.902

98.792

0.592
  cinA Streptococcus mitis SK321

49.409

100

0.505
  cinA Streptococcus pneumoniae Rx1

48.936

100

0.5
  cinA Streptococcus pneumoniae TIGR4

48.936

100

0.5
  cinA Streptococcus pneumoniae R6

48.936

100

0.5
  cinA Streptococcus pneumoniae D39

48.7

100

0.498
  cinA Streptococcus mitis NCTC 12261

48.7

100

0.498
  cinA Streptococcus mutans UA159

46.651

100

0.471
  cinA Streptococcus suis isolate S10

41.221

94.928

0.391

Multiple sequence alignment