Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3MT_RS13830 Genome accession   NZ_CP173557
Coordinates   2789847..2790503 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 98202     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2784847..2795503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3MT_RS13800 (ACI3MT_13800) yecA 2786098..2786763 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  ACI3MT_RS13820 (ACI3MT_13820) pgsA 2787413..2787961 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI3MT_RS13825 (ACI3MT_13825) uvrC 2788018..2789850 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACI3MT_RS13830 (ACI3MT_13830) letA 2789847..2790503 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI3MT_RS13835 (ACI3MT_13835) - 2790645..2790716 (+) 72 Protein_2701 transcriptional regulator -
  ACI3MT_RS13840 (ACI3MT_13840) yecU 2790799..2790975 (+) 177 WP_000590347.1 protein YecU -
  ACI3MT_RS13845 (ACI3MT_13845) yecF 2790962..2791186 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI3MT_RS13850 (ACI3MT_13850) sdiA 2791253..2791975 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  ACI3MT_RS13855 (ACI3MT_13855) tcyN 2792205..2792957 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI3MT_RS13860 (ACI3MT_13860) tcyL 2792954..2793622 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACI3MT_RS13865 (ACI3MT_13865) dcyD 2793637..2794623 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=960707 ACI3MT_RS13830 WP_000611335.1 2789847..2790503(-) (letA) [Escherichia coli strain 98202]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=960707 ACI3MT_RS13830 WP_000611335.1 2789847..2790503(-) (letA) [Escherichia coli strain 98202]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486