Detailed information NTG0095511

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: QMM33_RS06010
• Genome accession: NZ_AP025940
• Coordinates: 1184047..1184697 (-)
• Length: 216 a.a.
• NCBI ID: WP_001864147.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700204
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1179047..1189697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM33_RS05990 (PC0204_11740)	-	1179651..1180832 (-)	1182	WP_000655951.1	membrane protein	-
QMM33_RS05995 (PC0204_11750)	-	1180836..1181423 (-)	588	WP_000939886.1	ABC transporter ATP-binding protein	-
QMM33_RS06000 (PC0204_11760)	-	1181456..1181644 (-)	189	WP_050207196.1	hypothetical protein	-
QMM33_RS06005 (PC0204_11770)	comEC/celB	1181823..1184063 (-)	2241	WP_050207195.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
QMM33_RS06010 (PC0204_11780)	comEA/celA/cilE	1184047..1184697 (-)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
QMM33_RS06015 (PC0204_11790)	-	1184765..1185334 (-)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
QMM33_RS06020	ald	1185511..1186622 (+)	1112	Protein_1198	alanine dehydrogenase	-
QMM33_RS06025 (PC0204_11830)	-	1186923..1187249 (-)	327	Protein_1199	TfoX/Sxy family protein	-
QMM33_RS06030 (PC0204_11840)	-	1187252..1187752 (-)	501	WP_000566983.1	GNAT family N-acetyltransferase	-
QMM33_RS06035 (PC0204_11850)	-	1187945..1188913 (-)	969	WP_000658183.1	PhoH family protein	-
QMM33_RS06040 (PC0204_11860)	-	1188999..1189214 (-)	216	WP_001232082.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23205.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=95511 QMM33_RS06010 WP_001864147.1 1184047..1184697(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700204]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQVEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=95511 QMM33_RS06010 WP_001864147.1 1184047..1184697(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700204]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGTTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366