Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   QMM33_RS02495 Genome accession   NZ_AP025940
Coordinates   484584..486260 (-) Length   558 a.a.
NCBI ID   WP_318155894.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700204     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 479584..491260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM33_RS02465 (PC0204_04710) - 479918..480247 (-) 330 WP_050207112.1 hypothetical protein -
  QMM33_RS02470 (PC0204_04720) - 480524..480862 (+) 339 WP_050249616.1 LytTR family DNA-binding domain-containing protein -
  QMM33_RS02475 (PC0204_04730) comE/blpR 480867..481604 (+) 738 WP_001219145.1 response regulator transcription factor Regulator
  QMM33_RS02480 (PC0204_04740) - 481618..482958 (+) 1341 WP_050212001.1 sensor histidine kinase -
  QMM33_RS02485 (PC0204_04750) blpC 483000..483155 (-) 156 WP_044791640.1 quorum-sensing system pheromone BlpC -
  QMM33_RS02490 - 483212..484573 (-) 1362 Protein_492 bacteriocin secretion accessory protein -
  QMM33_RS02495 (PC0204_04780) comA/nlmT 484584..486260 (-) 1677 WP_318155894.1 peptide cleavage/export ABC transporter Regulator
  QMM33_RS10570 (PC0204_04790) comA/nlmT 486154..486741 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  QMM33_RS02500 (PC0204_04800) blpM 487023..487277 (+) 255 WP_001093256.1 two-peptide bacteriocin subunit BlpM -
  QMM33_RS02505 (PC0204_04810) blpN 487293..487496 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  QMM33_RS02510 (PC0204_04820) cipB 487740..487889 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  QMM33_RS02515 - 487993..488112 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  QMM33_RS02520 (PC0204_04830) - 488410..488574 (+) 165 WP_000727117.1 hypothetical protein -
  QMM33_RS02525 (PC0204_04840) - 488636..488974 (+) 339 WP_088804618.1 immunity protein -
  QMM33_RS02530 (PC0204_04860) - 489603..489986 (+) 384 WP_000877381.1 hypothetical protein -
  QMM33_RS02535 (PC0204_04870) - 490038..490727 (+) 690 WP_000760520.1 CPBP family intramembrane glutamic endopeptidase -
  QMM33_RS02540 (PC0204_04880) blpZ 490769..491017 (+) 249 WP_000276501.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 63022.34 Da        Isoelectric Point: 6.9397

>NTDB_id=95496 QMM33_RS02495 WP_318155894.1 484584..486260(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700204]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLRIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=95496 QMM33_RS02495 WP_318155894.1 484584..486260(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700204]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTC
TTATTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAAGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.711

99.821

0.726
  comA Streptococcus mitis NCTC 12261

67.025

100

0.67
  comA Streptococcus pneumoniae D39

66.667

100

0.667
  comA Streptococcus pneumoniae R6

66.667

100

0.667
  comA Streptococcus pneumoniae Rx1

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.369

100

0.665
  comA Streptococcus mitis SK321

66.487

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.308

100

0.663

Multiple sequence alignment