Detailed information NTG0095378

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: QMM10_RS08955
• Genome accession: NZ_AP025938
• Coordinates: 1766387..1767601 (-)
• Length: 404 a.a.
• NCBI ID: WP_281962104.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701057
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1767783..1769351	1766387..1767601	flank	182

Gene organization within MGE regions

Location: 1766387..1769351

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM10_RS08955 (PC1044_17530)	cinA	1766387..1767601 (-)	1215	WP_281962104.1	competence/damage-inducible protein A	Machinery gene
QMM10_RS08960 (PC1044_17540)	-	1767783..1769129 (-)	1347	WP_050207251.1	IS1380-like element ISSpn5 family transposase	-

Sequence

Protein

• Length: 404 a.a.
• Molecular weight: 43722.89 Da
• Isoelectric Point: 4.6303

>NTDB_id=95378 QMM10_RS08955 WP_281962104.1 1766387..1767601(-) (cinA) [Streptococcus pneumoniae strain PZ900701057]
MIWVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQ
AQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPMVLNQLLPKLMTGSK
LYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQILDCQTFEGISLRDF
CYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVRHIAVMHAFNLVRKA
LLSD

Nucleotide

• Length: 1215 bp

>NTDB_id=95378 QMM10_RS08955 WP_281962104.1 1766387..1767601(-) (cinA) [Streptococcus pneumoniae strain PZ900701057]
ATGATTTGGGTCAACACCAATGCCCAGTTTTTGTCGGAAAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGC
TGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTGAGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCG
GTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACCCTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAG
GCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACCAGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAAT
TGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGACTGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATG
TCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATGGTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAG
CTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGAGAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCA
GATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAGAAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAG
AGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATCTTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTT
TGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCATTGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGC
TGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCGTGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTT
TTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTGGATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCT
GAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAGCAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGC
AGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAGTCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCA
AGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGTCACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCT
TTATTAAGTGACTAA

Domains

Predicted by InterproScan.

• Competence-damaged protein (CinA) (248-400)

• Probable molybdopterin binding domain (MoCF_biosynth) (4-155)

• Damage-inducible protein CinA KH domain (CinA_KH) (163-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus pneumoniae TIGR4	99.751	99.257	0.99
cinA	Streptococcus pneumoniae Rx1	99.501	99.257	0.988
cinA	Streptococcus pneumoniae R6	99.501	99.257	0.988
cinA	Streptococcus pneumoniae D39	99.252	99.257	0.985
cinA	Streptococcus mitis SK321	93.516	99.257	0.928
cinA	Streptococcus mitis NCTC 12261	93.267	99.257	0.926
cinA	Streptococcus mutans UA159	70.075	99.257	0.696
cinA	Streptococcus suis isolate S10	53.383	98.762	0.527
cinA	Bacillus subtilis subsp. subtilis str. 168	44.14	99.257	0.438