Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   QML92_RS09330 Genome accession   NZ_AP025937
Coordinates   1825798..1826814 (-) Length   338 a.a.
NCBI ID   WP_078102766.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700792     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1820798..1831814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML92_RS09285 - 1820876..1821007 (-) 132 WP_000768904.1 hypothetical protein -
  QML92_RS09290 (PC0780_18130) - 1821008..1822198 (-) 1191 WP_000167766.1 acetate kinase -
  QML92_RS09295 (PC0780_18140) comYH 1822249..1823202 (-) 954 WP_000345100.1 class I SAM-dependent methyltransferase Machinery gene
  QML92_RS09300 - 1823263..1823857 (-) 595 Protein_1815 methyltransferase domain-containing protein -
  QML92_RS09305 (PC0780_18170) comGG/cglG 1823960..1824406 (-) 447 WP_001842224.1 competence type IV pilus minor pilin ComGG Machinery gene
  QML92_RS09310 comGF/cglF 1824384..1824845 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  QML92_RS09315 (PC0780_18190) comGE/cglE 1824808..1825110 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  QML92_RS09320 (PC0780_18200) comGD/cglD 1825073..1825477 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  QML92_RS09325 (PC0780_18210) comGC/cglC 1825470..1825796 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  QML92_RS09330 (PC0780_18220) comGB/cglB 1825798..1826814 (-) 1017 WP_078102766.1 competence type IV pilus assembly protein ComGB Machinery gene
  QML92_RS09335 (PC0780_18230) comGA/cglA/cilD 1826762..1827703 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  QML92_RS09340 (PC0780_18240) - 1827779..1828144 (-) 366 WP_000286415.1 DUF1033 family protein -
  QML92_RS09345 (PC0780_18250) - 1828295..1829353 (-) 1059 WP_000649470.1 zinc-dependent alcohol dehydrogenase family protein -
  QML92_RS09350 (PC0780_18260) nagA 1829516..1830667 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38455.45 Da        Isoelectric Point: 9.6162

>NTDB_id=95313 QML92_RS09330 WP_078102766.1 1825798..1826814(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700792]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVSRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=95313 QML92_RS09330 WP_078102766.1 1825798..1826814(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700792]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAGCCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.238

99.408

0.698
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment