Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   QML92_RS09315 Genome accession   NZ_AP025937
Coordinates   1824808..1825110 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700792     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1819808..1830110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML92_RS09280 (PC0780_18120) rnpA 1820488..1820859 (-) 372 WP_000739246.1 ribonuclease P protein component -
  QML92_RS09285 - 1820876..1821007 (-) 132 WP_000768904.1 hypothetical protein -
  QML92_RS09290 (PC0780_18130) - 1821008..1822198 (-) 1191 WP_000167766.1 acetate kinase -
  QML92_RS09295 (PC0780_18140) comYH 1822249..1823202 (-) 954 WP_000345100.1 class I SAM-dependent methyltransferase Machinery gene
  QML92_RS09300 - 1823263..1823857 (-) 595 Protein_1815 methyltransferase domain-containing protein -
  QML92_RS09305 (PC0780_18170) comGG/cglG 1823960..1824406 (-) 447 WP_001842224.1 competence type IV pilus minor pilin ComGG Machinery gene
  QML92_RS09310 comGF/cglF 1824384..1824845 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  QML92_RS09315 (PC0780_18190) comGE/cglE 1824808..1825110 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  QML92_RS09320 (PC0780_18200) comGD/cglD 1825073..1825477 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  QML92_RS09325 (PC0780_18210) comGC/cglC 1825470..1825796 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  QML92_RS09330 (PC0780_18220) comGB/cglB 1825798..1826814 (-) 1017 WP_078102766.1 competence type IV pilus assembly protein ComGB Machinery gene
  QML92_RS09335 (PC0780_18230) comGA/cglA/cilD 1826762..1827703 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  QML92_RS09340 (PC0780_18240) - 1827779..1828144 (-) 366 WP_000286415.1 DUF1033 family protein -
  QML92_RS09345 (PC0780_18250) - 1828295..1829353 (-) 1059 WP_000649470.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=95310 QML92_RS09315 WP_000413382.1 1824808..1825110(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700792]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=95310 QML92_RS09315 WP_000413382.1 1824808..1825110(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700792]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment