Detailed information NTG0940748

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: V6U68_RS09420
• Genome accession: NZ_CP145866
• Coordinates: 2016671..2017612 (-)
• Length: 313 a.a.
• NCBI ID: WP_201041167.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2018266..2019522	2016671..2017612	flank	654

Gene organization within MGE regions

Location: 2016671..2019522

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS09420 (V6U68_09400)	comYA	2016671..2017612 (-)	942	WP_201041167.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U68_RS09425 (V6U68_09405)	-	2017692..2018054 (-)	363	WP_073949471.1	DUF1033 family protein	-
V6U68_RS09430 (V6U68_09410)	-	2018266..2019515 (+)	1250	Protein_1801	ISL3 family transposase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35270.27 Da
• Isoelectric Point: 5.4492

>NTDB_id=940748 V6U68_RS09420 WP_201041167.1 2016671..2017612(-) (comYA) [Streptococcus salivarius strain KSS9]
MVTEFAKEMIKNADSCGAQDIYVIPRQDTYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide

• Length: 942 bp

>NTDB_id=940748 V6U68_RS09420 WP_201041167.1 2016671..2017612(-) (comYA) [Streptococcus salivarius strain KSS9]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATACTTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACTGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCTGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGTCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus mutans UA159	65.176	100	0.652
comYA	Streptococcus mutans UA140	65.176	100	0.652
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.595	99.361	0.652
comGA/cglA/cilD	Streptococcus pneumoniae D39	64.309	99.361	0.639
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	64.309	99.361	0.639
comGA/cglA/cilD	Streptococcus pneumoniae R6	64.309	99.361	0.639
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	64.309	99.361	0.639
comYA	Streptococcus gordonii str. Challis substr. CH1	62.939	100	0.629
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	60.897	99.681	0.607
comGA	Lactococcus lactis subsp. cremoris KW2	51.447	99.361	0.511
comGA	Latilactobacillus sakei subsp. sakei 23K	41.697	86.581	0.361