Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   V6U66_RS02610 Genome accession   NZ_CP145864
Coordinates   494678..494863 (+) Length   61 a.a.
NCBI ID   WP_410534556.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 494926..511795 494678..494863 flank 63


Gene organization within MGE regions


Location: 494678..511795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS02610 (V6U66_02615) prx 494678..494863 (+) 186 WP_410534556.1 Paratox Regulator
  V6U66_RS02615 (V6U66_02620) - 494926..495612 (-) 687 WP_410534646.1 sensor histidine kinase -
  V6U66_RS02620 - 495630..495680 (+) 51 WP_410534648.1 hypothetical protein -
  V6U66_RS02625 (V6U66_02625) - 495687..496295 (+) 609 WP_410534557.1 hypothetical protein -
  V6U66_RS02630 (V6U66_02630) - 496375..496842 (+) 468 WP_045772495.1 8-oxo-dGTP diphosphatase -
  V6U66_RS02635 (V6U66_02635) - 497657..498274 (+) 618 WP_005376691.1 SAP domain-containing protein -
  V6U66_RS02640 (V6U66_02640) - 498657..499865 (-) 1209 WP_045772496.1 ATP-binding protein -
  V6U66_RS02645 (V6U66_02645) - 500208..500729 (+) 522 WP_045772497.1 DUF2975 domain-containing protein -
  V6U66_RS02650 (V6U66_02650) - 500734..500958 (+) 225 WP_045772572.1 helix-turn-helix domain-containing protein -
  V6U66_RS02655 (V6U66_02655) - 500948..501400 (+) 453 WP_045772498.1 hypothetical protein -
  V6U66_RS02660 (V6U66_02660) - 501985..502242 (+) 258 WP_084869014.1 hypothetical protein -
  V6U66_RS02665 (V6U66_02665) - 502367..503332 (-) 966 WP_197092265.1 IS3 family transposase -
  V6U66_RS02670 (V6U66_02670) - 503329..504006 (-) 678 WP_002890056.1 helix-turn-helix domain-containing protein -
  V6U66_RS02675 (V6U66_02675) prx 504150..504335 (+) 186 WP_045772500.1 Paratox Regulator
  V6U66_RS02680 (V6U66_02680) - 504810..505250 (+) 441 WP_410534558.1 helix-turn-helix domain-containing protein -
  V6U66_RS02685 (V6U66_02690) - 505784..506281 (-) 498 WP_045772502.1 GNAT family N-acetyltransferase -
  V6U66_RS02690 (V6U66_02695) - 506312..506455 (-) 144 WP_158084825.1 hypothetical protein -
  V6U66_RS02695 (V6U66_02700) - 506582..507664 (+) 1083 WP_410534559.1 hypothetical protein -
  V6U66_RS02700 (V6U66_02705) - 507696..508094 (+) 399 WP_410534560.1 hypothetical protein -
  V6U66_RS02705 (V6U66_02710) - 508106..508507 (+) 402 WP_410534561.1 hypothetical protein -
  V6U66_RS02710 (V6U66_02715) - 508508..510451 (+) 1944 WP_410534562.1 AAA family ATPase -
  V6U66_RS02715 (V6U66_02720) - 510525..510872 (+) 348 WP_073689792.1 hypothetical protein -
  V6U66_RS02720 (V6U66_02725) - 510893..511225 (+) 333 WP_410534563.1 hypothetical protein -
  V6U66_RS02725 (V6U66_02730) tnpA 511322..511795 (-) 474 WP_002891962.1 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 61 a.a.        Molecular weight: 7125.13 Da        Isoelectric Point: 4.2182

>NTDB_id=940567 V6U66_RS02610 WP_410534556.1 494678..494863(+) (prx) [Streptococcus salivarius strain KSS7]
MITYDEVMEAIERGFIKGDKISIVRRNGKIHDYVLPGEKVESEEIVEKEDLDVVLEELKEF

Nucleotide


Download         Length: 186 bp        

>NTDB_id=940567 V6U66_RS02610 WP_410534556.1 494678..494863(+) (prx) [Streptococcus salivarius strain KSS7]
ATGATAACATATGATGAAGTAATGGAAGCGATAGAAAGAGGGTTTATCAAGGGCGATAAAATCAGCATTGTCCGACGAAA
TGGGAAGATTCATGATTATGTTTTACCAGGAGAGAAAGTAGAATCTGAAGAAATAGTGGAAAAAGAGGACTTAGATGTTG
TCCTTGAAGAGTTGAAGGAGTTCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

55.172

95.082

0.525
  prx Streptococcus pyogenes MGAS8232

55.172

95.082

0.525
  prx Streptococcus pyogenes MGAS315

53.448

95.082

0.508
  prx Streptococcus pyogenes MGAS315

51.724

95.082

0.492
  prx Streptococcus pyogenes MGAS315

60.465

70.492

0.426
  prx Streptococcus pyogenes MGAS315

58.14

70.492

0.41
  prx Streptococcus pyogenes MGAS315

54.762

68.852

0.377