Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   V6U66_RS02675 Genome accession   NZ_CP145864
Coordinates   504150..504335 (+) Length   61 a.a.
NCBI ID   WP_045772500.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 494926..511795 504150..504335 within 0


Gene organization within MGE regions


Location: 494926..511795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS02615 (V6U66_02620) - 494926..495612 (-) 687 WP_410534646.1 sensor histidine kinase -
  V6U66_RS02620 - 495630..495680 (+) 51 WP_410534648.1 hypothetical protein -
  V6U66_RS02625 (V6U66_02625) - 495687..496295 (+) 609 WP_410534557.1 hypothetical protein -
  V6U66_RS02630 (V6U66_02630) - 496375..496842 (+) 468 WP_045772495.1 8-oxo-dGTP diphosphatase -
  V6U66_RS02635 (V6U66_02635) - 497657..498274 (+) 618 WP_005376691.1 SAP domain-containing protein -
  V6U66_RS02640 (V6U66_02640) - 498657..499865 (-) 1209 WP_045772496.1 ATP-binding protein -
  V6U66_RS02645 (V6U66_02645) - 500208..500729 (+) 522 WP_045772497.1 DUF2975 domain-containing protein -
  V6U66_RS02650 (V6U66_02650) - 500734..500958 (+) 225 WP_045772572.1 helix-turn-helix domain-containing protein -
  V6U66_RS02655 (V6U66_02655) - 500948..501400 (+) 453 WP_045772498.1 hypothetical protein -
  V6U66_RS02660 (V6U66_02660) - 501985..502242 (+) 258 WP_084869014.1 hypothetical protein -
  V6U66_RS02665 (V6U66_02665) - 502367..503332 (-) 966 WP_197092265.1 IS3 family transposase -
  V6U66_RS02670 (V6U66_02670) - 503329..504006 (-) 678 WP_002890056.1 helix-turn-helix domain-containing protein -
  V6U66_RS02675 (V6U66_02675) prx 504150..504335 (+) 186 WP_045772500.1 Paratox Regulator
  V6U66_RS02680 (V6U66_02680) - 504810..505250 (+) 441 WP_410534558.1 helix-turn-helix domain-containing protein -
  V6U66_RS02685 (V6U66_02690) - 505784..506281 (-) 498 WP_045772502.1 GNAT family N-acetyltransferase -
  V6U66_RS02690 (V6U66_02695) - 506312..506455 (-) 144 WP_158084825.1 hypothetical protein -
  V6U66_RS02695 (V6U66_02700) - 506582..507664 (+) 1083 WP_410534559.1 hypothetical protein -
  V6U66_RS02700 (V6U66_02705) - 507696..508094 (+) 399 WP_410534560.1 hypothetical protein -
  V6U66_RS02705 (V6U66_02710) - 508106..508507 (+) 402 WP_410534561.1 hypothetical protein -
  V6U66_RS02710 (V6U66_02715) - 508508..510451 (+) 1944 WP_410534562.1 AAA family ATPase -
  V6U66_RS02715 (V6U66_02720) - 510525..510872 (+) 348 WP_073689792.1 hypothetical protein -
  V6U66_RS02720 (V6U66_02725) - 510893..511225 (+) 333 WP_410534563.1 hypothetical protein -
  V6U66_RS02725 (V6U66_02730) tnpA 511322..511795 (-) 474 WP_002891962.1 IS200/IS605 family transposase -

Sequence


Protein


Download         Length: 61 a.a.        Molecular weight: 7005.07 Da        Isoelectric Point: 4.3566

>NTDB_id=940568 V6U66_RS02675 WP_045772500.1 504150..504335(+) (prx) [Streptococcus salivarius strain KSS7]
MMTYDEVLEAIGRGFIKGDKISIIRRNGKIHDYVLPGEKVEPGEIVEKEDLDVVLEELKEF

Nucleotide


Download         Length: 186 bp        

>NTDB_id=940568 V6U66_RS02675 WP_045772500.1 504150..504335(+) (prx) [Streptococcus salivarius strain KSS7]
ATGATGACTTATGATGAAGTACTGGAAGCGATAGGAAGAGGGTTTATCAAGGGAGATAAAATCAGTATTATTCGACGAAA
TGGCAAGATCCATGATTATGTTTTACCAGGAGAGAAAGTAGAACCTGGAGAAATAGTGGAAAAAGAGGACTTAGATGTTG
TCCTTGAAGAGTTGAAGGAGTTCTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

54.237

96.721

0.525

  prx Streptococcus pyogenes MGAS8232

55.172

95.082

0.525

  prx Streptococcus pyogenes MGAS315

51.724

95.082

0.492

  prx Streptococcus pyogenes MGAS315

50

95.082

0.475

  prx Streptococcus pyogenes MGAS315

60.465

70.492

0.426

  prx Streptococcus pyogenes MGAS315

60

65.574

0.393

  prx Streptococcus pyogenes MGAS315

53.488

70.492

0.377