Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AAX72_RS09055 Genome accession   NZ_CP145109
Coordinates   1798887..1800137 (+) Length   416 a.a.
NCBI ID   WP_047021267.1    Uniprot ID   -
Organism   Levilactobacillus brevis strain 47f     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1793887..1805137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAX72_RS09035 (AAX72_009035) - 1794601..1795896 (+) 1296 WP_047021268.1 pitrilysin family protein -
  AAX72_RS09040 (AAX72_009040) - 1795874..1797163 (+) 1290 WP_021742877.1 pitrilysin family protein -
  AAX72_RS09045 (AAX72_009045) - 1797277..1798182 (+) 906 WP_011668110.1 helix-turn-helix domain-containing protein -
  AAX72_RS09050 (AAX72_009050) pgsA 1798244..1798831 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AAX72_RS09055 (AAX72_009055) cinA 1798887..1800137 (+) 1251 WP_047021267.1 competence/damage-inducible protein A Machinery gene
  AAX72_RS09060 (AAX72_009060) recA 1800231..1801364 (+) 1134 WP_043023201.1 recombinase RecA Machinery gene
  AAX72_RS09065 (AAX72_009065) - 1801480..1802742 (-) 1263 WP_035465312.1 ISL3 family transposase -
  AAX72_RS09070 (AAX72_009070) - 1802894..1803046 (-) 153 WP_172757682.1 hypothetical protein -
  AAX72_RS09075 (AAX72_009075) rny 1803374..1804933 (+) 1560 WP_011667971.1 ribonuclease Y -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44805.95 Da        Isoelectric Point: 5.5043

>NTDB_id=937226 AAX72_RS09055 WP_047021267.1 1798887..1800137(+) (cinA) [Levilactobacillus brevis strain 47f]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRKGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=937226 AAX72_RS09055 WP_047021267.1 1798887..1800137(+) (cinA) [Levilactobacillus brevis strain 47f]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGAAGGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGACAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.325

99.76

0.512
  cinA Streptococcus mitis SK321

49.524

100

0.5
  cinA Streptococcus mitis NCTC 12261

49.406

100

0.5
  cinA Streptococcus pneumoniae TIGR4

48.456

100

0.49
  cinA Streptococcus pneumoniae Rx1

48.456

100

0.49
  cinA Streptococcus pneumoniae R6

48.456

100

0.49
  cinA Streptococcus pneumoniae D39

48.219

100

0.488
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445