Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   VW923_RS13135 Genome accession   NZ_CP142827
Coordinates   2663577..2664821 (-) Length   414 a.a.
NCBI ID   WP_010716771.1    Uniprot ID   -
Organism   Enterococcus faecalis strain CF4A-3113     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2658577..2669821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VW923_RS13115 (VW923_13115) - 2659047..2659433 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  VW923_RS13120 (VW923_13120) - 2659507..2660304 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  VW923_RS13125 (VW923_13125) rny 2660464..2662020 (-) 1557 WP_002354863.1 ribonuclease Y -
  VW923_RS13130 (VW923_13130) recA 2662417..2663463 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  VW923_RS13135 (VW923_13135) cinA 2663577..2664821 (-) 1245 WP_010716771.1 competence/damage-inducible protein A Machinery gene
  VW923_RS13140 (VW923_13140) - 2665013..2666212 (+) 1200 WP_002398187.1 hypothetical protein -
  VW923_RS13145 (VW923_13145) - 2666292..2666921 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  VW923_RS13150 (VW923_13150) - 2666980..2667405 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  VW923_RS13155 (VW923_13155) - 2667494..2667877 (-) 384 WP_002358999.1 YccF domain-containing protein -
  VW923_RS13160 (VW923_13160) - 2668041..2668832 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45200.28 Da        Isoelectric Point: 4.6195

>NTDB_id=927194 VW923_RS13135 WP_010716771.1 2663577..2664821(-) (cinA) [Enterococcus faecalis strain CF4A-3113]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIESGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIANQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=927194 VW923_RS13135 WP_010716771.1 2663577..2664821(-) (cinA) [Enterococcus faecalis strain CF4A-3113]
ATGAAAGCAGAAATTATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGACGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTATGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAAGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGAACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGACGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mutans UA159

52.153

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.276

98.068

0.473
  cinA Streptococcus suis isolate S10

43.796

99.275

0.435