NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	AB1F71_RS02985	Genome accession	NZ_CP160386
Coordinates	581874..582551 (+)	Length	225 a.a.
NCBI ID	WP_002261916.1	Uniprot ID	Q8DV80
Organism	Streptococcus mutans strain UA159 ykuR deletion
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 576874..587551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F71_RS02965 (AB1F71_02965)	-	578241..579260 (-)	1020	WP_002261920.1	GIY-YIG nuclease family protein	-
AB1F71_RS02970 (AB1F71_02970)	-	579306..579818 (-)	513	WP_002261919.1	HXXEE domain-containing protein	-
AB1F71_RS02975 (AB1F71_02975)	-	579907..580842 (-)	936	WP_002261918.1	polysaccharide deacetylase family protein	-
AB1F71_RS02980 (AB1F71_02980)	-	580981..581733 (+)	753	WP_002261917.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
AB1F71_RS02985 (AB1F71_02985)	comEA/celA/cilE	581874..582551 (+)	678	WP_002261916.1	helix-hairpin-helix domain-containing protein	Machinery gene
AB1F71_RS02990 (AB1F71_02990)	comEC/celB	582541..584775 (+)	2235	WP_002261915.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AB1F71_RS02995 (AB1F71_02995)	-	584961..585587 (+)	627	WP_002261914.1	DUF805 domain-containing protein	-
AB1F71_RS03000 (AB1F71_03000)	holA	585755..586795 (+)	1041	WP_002261913.1	DNA polymerase III subunit delta	-

Sequence

Protein

Download Length: 225 a.a. Molecular weight: 24459.77 Da Isoelectric Point: 8.2999

                                >NTDB_id=918004 AB1F71_RS02985 WP_002261916.1 581874..582551(+) (comEA/celA/cilE) [Streptococcus mutans strain UA159 ykuR deletion]

MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQTTAKSTITVDIKG

AVKHEGVYTLPIDSRINDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETSV

KGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide

Download Length: 678 bp

                                >NTDB_id=918004 AB1F71_RS02985 WP_002261916.1 581874..582551(+) (comEA/celA/cilE) [Streptococcus mutans strain UA159 ykuR deletion]

ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCCCTAGTTGGTGGTCTTGTAGTCTTACTGGG

TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG

TAACCACAAAGACTGGCAAAGAAAGTCAGAAGAAGACGCAGACGACTGCCAAATCAACAATAACTGTTGATATTAAAGGA

GCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTAATGATGTAATAGAAAAAGCGGGAGGTTTTTC

TGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTGGTG

AGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCGGTA

AAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCAGGA

TATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATAAAA

CATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(162-222)

SLBB domain (SLBB)

(76-129)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q8DV80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.612	100	0.44
comEA/celA/cilE	Streptococcus mitis NCTC 12261	43.612	100	0.44
comEA/celA/cilE	Streptococcus pneumoniae R6	42.731	100	0.431
comEA/celA/cilE	Streptococcus pneumoniae D39	42.731	100	0.431
comEA/celA/cilE	Streptococcus pneumoniae Rx1	42.731	100	0.431
comEA/celA/cilE	Streptococcus mitis SK321	42.291	100	0.427
comEA	Lactococcus lactis subsp. cremoris KW2	42.222	100	0.422
comEA	Streptococcus thermophilus LMD-9	57.143	68.444	0.391
comEA	Latilactobacillus sakei subsp. sakei 23K	35.124	100	0.378
comEA	Bacillus subtilis subsp. subtilis str. 168	37.273	97.778	0.364

Detailed information NTG0918004