Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | U6038_RS03360 | Genome accession | NZ_CP140715 |
| Coordinates | 696977..698098 (-) | Length | 373 a.a. |
| NCBI ID | WP_333655316.1 | Uniprot ID | - |
| Organism | Acinetobacter johnsonii strain FAHZZU3110hy | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 681852..743772 | 696977..698098 | within | 0 |
Gene organization within MGE regions
Location: 681852..743772
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| U6038_RS03275 (U6038_03275) | - | 682109..682396 (-) | 288 | WP_004694907.1 | PA4642 family protein | - |
| U6038_RS03280 (U6038_03280) | minE | 682518..682790 (-) | 273 | WP_004694905.1 | cell division topological specificity factor MinE | - |
| U6038_RS03285 (U6038_03285) | minD | 682793..683605 (-) | 813 | WP_010326008.1 | septum site-determining protein MinD | - |
| U6038_RS03290 (U6038_03290) | minC | 683675..684406 (-) | 732 | WP_125281218.1 | septum site-determining protein MinC | - |
| U6038_RS03295 (U6038_03295) | - | 684530..685579 (-) | 1050 | WP_374758889.1 | preprotein translocase subunit SecA | - |
| U6038_RS03300 (U6038_03300) | - | 685590..686522 (-) | 933 | WP_279679100.1 | acyltransferase | - |
| U6038_RS03305 (U6038_03305) | - | 686779..687429 (+) | 651 | WP_010326012.1 | OmpA family protein | - |
| U6038_RS03310 (U6038_03310) | - | 687556..689595 (+) | 2040 | WP_004694892.1 | UvrD-helicase domain-containing protein | - |
| U6038_RS03315 (U6038_03315) | dut | 689639..690091 (+) | 453 | WP_004694889.1 | dUTP diphosphatase | - |
| U6038_RS03320 (U6038_03320) | - | 690288..691715 (+) | 1428 | WP_333655310.1 | phosphomannomutase/phosphoglucomutase | - |
| U6038_RS03325 (U6038_03325) | argB | 691726..692628 (+) | 903 | WP_058869034.1 | acetylglutamate kinase | - |
| U6038_RS03330 (U6038_03330) | - | 692797..693645 (+) | 849 | WP_333655313.1 | class II glutamine amidotransferase | - |
| U6038_RS03335 (U6038_03335) | - | 693920..694375 (+) | 456 | WP_005400160.1 | bacteriohemerythrin | - |
| U6038_RS03340 (U6038_03340) | - | 694518..695600 (+) | 1083 | WP_058869036.1 | hypothetical protein | - |
| U6038_RS03345 (U6038_03345) | - | 695600..695923 (+) | 324 | WP_010326018.1 | RnfH family protein | - |
| U6038_RS03350 (U6038_03350) | - | 695970..696368 (-) | 399 | WP_004694868.1 | outer membrane protein assembly factor BamE | - |
| U6038_RS03355 (U6038_03355) | fur | 696481..696918 (+) | 438 | WP_004694866.1 | ferric iron uptake transcriptional regulator | - |
| U6038_RS03360 (U6038_03360) | pilU | 696977..698098 (-) | 1122 | WP_333655316.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| U6038_RS03365 (U6038_03365) | pilT | 698125..699162 (-) | 1038 | WP_004694862.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| U6038_RS03370 (U6038_03370) | - | 699285..699974 (+) | 690 | WP_125281224.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| U6038_RS03375 (U6038_03375) | - | 700165..700899 (+) | 735 | WP_148826638.1 | hypothetical protein | - |
| U6038_RS03380 (U6038_03380) | - | 701016..704612 (-) | 3597 | WP_333655320.1 | AAA family ATPase | - |
| U6038_RS03385 (U6038_03385) | - | 704622..705875 (-) | 1254 | WP_333655323.1 | exonuclease SbcCD subunit D | - |
| U6038_RS03390 (U6038_03390) | - | 706273..707250 (+) | 978 | WP_333655325.1 | sensor domain-containing diguanylate cyclase | - |
| U6038_RS03395 (U6038_03395) | - | 707585..708037 (+) | 453 | WP_125281229.1 | ABZJ_00895 family protein | - |
| U6038_RS03400 (U6038_03400) | - | 708091..708990 (+) | 900 | WP_205667061.1 | TIGR01777 family oxidoreductase | - |
| U6038_RS03405 (U6038_03405) | thiO | 709019..710128 (-) | 1110 | WP_333655329.1 | glycine oxidase ThiO | - |
| U6038_RS03410 (U6038_03410) | hemB | 710156..711169 (-) | 1014 | WP_058869046.1 | porphobilinogen synthase | - |
| U6038_RS03415 (U6038_03415) | - | 711278..711775 (+) | 498 | WP_004694841.1 | thioesterase family protein | - |
| U6038_RS03420 (U6038_03420) | - | 712023..713174 (+) | 1152 | WP_279687755.1 | efflux RND transporter periplasmic adaptor subunit | - |
| U6038_RS03425 (U6038_03425) | - | 713181..714710 (+) | 1530 | WP_058869049.1 | DHA2 family efflux MFS transporter permease subunit | - |
| U6038_RS03430 (U6038_03430) | glpK | 714807..716291 (-) | 1485 | WP_333655335.1 | glycerol kinase GlpK | - |
| U6038_RS03440 (U6038_03440) | - | 716963..718099 (+) | 1137 | WP_333655337.1 | tyrosine-type recombinase/integrase | - |
| U6038_RS03445 (U6038_03445) | - | 718226..719038 (-) | 813 | WP_333655340.1 | hypothetical protein | - |
| U6038_RS03450 (U6038_03450) | - | 719293..721644 (+) | 2352 | WP_333655343.1 | hypothetical protein | - |
| U6038_RS03455 (U6038_03455) | - | 722175..723101 (+) | 927 | WP_333655346.1 | YagK/YfjJ domain-containing protein | - |
| U6038_RS03460 (U6038_03460) | - | 723185..724138 (+) | 954 | WP_333655349.1 | hypothetical protein | - |
| U6038_RS03465 (U6038_03465) | - | 724288..724515 (+) | 228 | WP_333655352.1 | helix-turn-helix transcriptional regulator | - |
| U6038_RS03470 (U6038_03470) | - | 724548..724766 (-) | 219 | WP_333655355.1 | hypothetical protein | - |
| U6038_RS03475 (U6038_03475) | - | 725456..726664 (+) | 1209 | WP_333655358.1 | hypothetical protein | - |
| U6038_RS03480 (U6038_03480) | - | 726815..727186 (+) | 372 | WP_333655362.1 | hypothetical protein | - |
| U6038_RS03485 (U6038_03485) | - | 727339..727659 (+) | 321 | WP_184117949.1 | hypothetical protein | - |
| U6038_RS03490 (U6038_03490) | - | 727724..728770 (+) | 1047 | WP_333655366.1 | DUF932 domain-containing protein | - |
| U6038_RS03495 (U6038_03495) | - | 728914..729957 (+) | 1044 | WP_178905318.1 | YqaJ viral recombinase family protein | - |
| U6038_RS03500 (U6038_03500) | - | 730074..731006 (+) | 933 | WP_279681078.1 | hydrolase or metal-binding protein | - |
| U6038_RS03505 (U6038_03505) | - | 731074..731304 (+) | 231 | WP_016167128.1 | helix-turn-helix transcriptional regulator | - |
| U6038_RS03510 (U6038_03510) | - | 731335..731559 (+) | 225 | Protein_667 | hypothetical protein | - |
| U6038_RS03515 (U6038_03515) | - | 731640..734477 (+) | 2838 | WP_279681077.1 | SNF2-related protein | - |
| U6038_RS03520 (U6038_03520) | - | 734520..734792 (+) | 273 | WP_106439006.1 | hypothetical protein | - |
| U6038_RS03525 (U6038_03525) | - | 734851..736980 (-) | 2130 | WP_333655378.1 | nuclease-related domain-containing DEAD/DEAH box helicase | - |
| U6038_RS03530 (U6038_03530) | - | 737173..740301 (+) | 3129 | WP_333655380.1 | site-specific DNA-methyltransferase | - |
| U6038_RS03535 (U6038_03535) | - | 740308..743730 (+) | 3423 | WP_333655382.1 | DEAD/DEAH box helicase family protein | - |
Sequence
Protein
Download Length: 373 a.a. Molecular weight: 41830.07 Da Isoelectric Point: 6.5784
>NTDB_id=915116 U6038_RS03360 WP_333655316.1 696977..698098(-) (pilU) [Acinetobacter johnsonii strain FAHZZU3110hy]
MDFNDLLNYMIQQKASDLFITADVEPSMKINGQIVPVAKGKLTGDVAGQLLNSIMSDKQRKEFADTHECNFAIMNRDKTA
RFRVSAFQQRDMPGMVLRRIETQIPTMDELKLPPVLKELAMTKRGIIIFVGATGTGKSTSLASIIGYRNQNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSRETMDYAIAFAETGHLVFATLHANNANQAIDR
IIHFFEADRHSQLFMDLSLNLKAMVAQQLIPTPDGNSRRAAIEILINSPLISDLIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAKQITYKDALKHADSPNDLRLQIKLSEEGGDRLLHASANITFDGQA
MDFNDLLNYMIQQKASDLFITADVEPSMKINGQIVPVAKGKLTGDVAGQLLNSIMSDKQRKEFADTHECNFAIMNRDKTA
RFRVSAFQQRDMPGMVLRRIETQIPTMDELKLPPVLKELAMTKRGIIIFVGATGTGKSTSLASIIGYRNQNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSRETMDYAIAFAETGHLVFATLHANNANQAIDR
IIHFFEADRHSQLFMDLSLNLKAMVAQQLIPTPDGNSRRAAIEILINSPLISDLIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAKQITYKDALKHADSPNDLRLQIKLSEEGGDRLLHASANITFDGQA
Nucleotide
Download Length: 1122 bp
>NTDB_id=915116 U6038_RS03360 WP_333655316.1 696977..698098(-) (pilU) [Acinetobacter johnsonii strain FAHZZU3110hy]
ATGGATTTTAACGACTTACTCAATTATATGATTCAACAAAAAGCGTCGGATTTATTTATCACCGCTGATGTTGAACCCTC
CATGAAAATTAACGGTCAAATTGTGCCTGTGGCTAAGGGTAAGCTGACGGGTGATGTCGCGGGGCAACTGCTCAACTCGA
TTATGAGTGACAAGCAGCGTAAAGAATTTGCAGATACACATGAGTGCAACTTCGCGATTATGAATCGGGATAAAACTGCA
CGTTTTCGTGTCAGTGCCTTTCAACAGCGTGATATGCCAGGTATGGTTTTGCGTCGAATTGAGACGCAAATTCCAACCAT
GGATGAGTTAAAACTCCCGCCTGTACTCAAAGAGTTAGCCATGACCAAACGTGGCATCATTATCTTTGTGGGTGCAACTG
GTACAGGTAAATCGACCTCTTTGGCTTCGATCATTGGTTACCGTAACCAAAACTCGAAAGGTCATATCATTACCATTGAA
GACCCGATTGAATTTATTCATGAGCATGCAGGCTGTATCATTACCCAGCGTGAAGTGGGCATTGATACAGACTCTTTTGA
AATCGCGCTGAAAAACACCTTACGTCAGGCACCCGATGTGATCCTGATTGGTGAGATTCGTTCCCGCGAAACCATGGATT
ATGCAATTGCCTTTGCTGAAACAGGTCACTTGGTATTTGCAACGCTACACGCCAACAACGCCAACCAAGCCATCGACCGT
ATTATTCACTTTTTTGAAGCAGACCGTCATAGCCAATTGTTTATGGACTTGTCTTTAAACCTTAAAGCGATGGTTGCTCA
GCAGTTGATTCCAACACCTGACGGTAATTCACGTCGCGCTGCAATTGAGATTTTGATTAACTCACCGTTAATTTCCGATT
TGATCCGTAAAGGTGAAATCCACGAAATTAAAGACCTGATGAAGCGTTCTCGTGAACTCGGTATGCAAACCTTTGACCAA
GCCTTATTCGATTTGTACAAAGCTAAGCAGATTACCTATAAAGATGCGCTGAAACACGCCGACTCTCCAAACGACTTACG
CTTACAAATCAAGTTGTCCGAAGAAGGCGGTGATCGTCTATTGCATGCCAGTGCAAACATCACGTTTGACGGACAAGCTT
AA
ATGGATTTTAACGACTTACTCAATTATATGATTCAACAAAAAGCGTCGGATTTATTTATCACCGCTGATGTTGAACCCTC
CATGAAAATTAACGGTCAAATTGTGCCTGTGGCTAAGGGTAAGCTGACGGGTGATGTCGCGGGGCAACTGCTCAACTCGA
TTATGAGTGACAAGCAGCGTAAAGAATTTGCAGATACACATGAGTGCAACTTCGCGATTATGAATCGGGATAAAACTGCA
CGTTTTCGTGTCAGTGCCTTTCAACAGCGTGATATGCCAGGTATGGTTTTGCGTCGAATTGAGACGCAAATTCCAACCAT
GGATGAGTTAAAACTCCCGCCTGTACTCAAAGAGTTAGCCATGACCAAACGTGGCATCATTATCTTTGTGGGTGCAACTG
GTACAGGTAAATCGACCTCTTTGGCTTCGATCATTGGTTACCGTAACCAAAACTCGAAAGGTCATATCATTACCATTGAA
GACCCGATTGAATTTATTCATGAGCATGCAGGCTGTATCATTACCCAGCGTGAAGTGGGCATTGATACAGACTCTTTTGA
AATCGCGCTGAAAAACACCTTACGTCAGGCACCCGATGTGATCCTGATTGGTGAGATTCGTTCCCGCGAAACCATGGATT
ATGCAATTGCCTTTGCTGAAACAGGTCACTTGGTATTTGCAACGCTACACGCCAACAACGCCAACCAAGCCATCGACCGT
ATTATTCACTTTTTTGAAGCAGACCGTCATAGCCAATTGTTTATGGACTTGTCTTTAAACCTTAAAGCGATGGTTGCTCA
GCAGTTGATTCCAACACCTGACGGTAATTCACGTCGCGCTGCAATTGAGATTTTGATTAACTCACCGTTAATTTCCGATT
TGATCCGTAAAGGTGAAATCCACGAAATTAAAGACCTGATGAAGCGTTCTCGTGAACTCGGTATGCAAACCTTTGACCAA
GCCTTATTCGATTTGTACAAAGCTAAGCAGATTACCTATAAAGATGCGCTGAAACACGCCGACTCTCCAAACGACTTACG
CTTACAAATCAAGTTGTCCGAAGAAGGCGGTGATCGTCTATTGCATGCCAGTGCAAACATCACGTTTGACGGACAAGCTT
AA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
76.984 |
100 |
0.78 |
| pilU | Pseudomonas stutzeri DSM 10701 |
68.194 |
99.464 |
0.678 |
| pilU | Vibrio cholerae strain A1552 |
55.135 |
99.196 |
0.547 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
41.908 |
92.761 |
0.389 |
| pilT | Legionella pneumophila strain Lp02 |
41.42 |
90.617 |
0.375 |
| pilT | Legionella pneumophila strain ERS1305867 |
41.42 |
90.617 |
0.375 |
| pilT | Pseudomonas aeruginosa PAK |
39.306 |
92.761 |
0.365 |