Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   L6419_RS00375 Genome accession   NZ_AP025332
Coordinates   59039..60409 (+) Length   456 a.a.
NCBI ID   WP_336512672.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 54039..65409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS00340 (GUT184_00490) - 54170..54322 (+) 153 WP_155962529.1 hypothetical protein -
  L6419_RS00345 (GUT184_00500) - 55320..55514 (+) 195 WP_155963542.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6419_RS00350 (GUT184_00510) - 55529..55717 (+) 189 WP_155963541.1 hypothetical protein -
  L6419_RS00355 (GUT184_00520) - 55721..55876 (+) 156 WP_156020754.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6419_RS00360 (GUT184_00530) - 55931..56122 (+) 192 WP_024533166.1 hypothetical protein -
  L6419_RS00365 - 56388..56534 (+) 147 WP_237375471.1 hypothetical protein -
  L6419_RS00370 (GUT184_00540) comA 56880..59033 (+) 2154 WP_237375472.1 peptide cleavage/export ABC transporter ComA Regulator
  L6419_RS00375 (GUT184_00550) comB 59039..60409 (+) 1371 WP_336512672.1 bacteriocin secretion accessory protein Regulator
  L6419_RS00380 (GUT184_00560) ruvB 60840..61838 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  L6419_RS00385 (GUT184_00570) - 62010..62633 (+) 624 WP_237375766.1 HAD-IA family hydrolase -
  L6419_RS00390 (GUT184_00580) comR 62736..63635 (+) 900 WP_024532318.1 helix-turn-helix domain-containing protein Regulator
  L6419_RS00395 (GUT184_00590) - 63851..65077 (+) 1227 WP_237374189.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50649.32 Da        Isoelectric Point: 5.7393

>NTDB_id=91158 L6419_RS00375 WP_336512672.1 59039..60409(+) (comB) [Streptococcus ruminantium strain GUT-184]
MMEHQLLESGEFYHRRYHNAASRVILPSFALLVFLMMFAFFAKKELTVVTRATVEPLHVLSKIQSTSNNPIKMNYLKENQ
EVAVGDVLVEYQSSSEQIQEEGIKKKITLLKEQLSQLELLKKSLESGENQFPQEDKYGYSQSFVDYRNKLLTLESNVEQQ
NTTIAAQNAAISQSQMELGNIVKTSQKALSDYKNLRMAIQSDAEISEDNAGYSLYVGYTTQLSQATGIAEKTTLKQQMLT
QLDNQISQLENQLATYRVQYAGAGAQQAYATNLDSQSASLKSQYLTKVAQEWTSLTSQLGELEGTLGLQENMRAKTKIVA
NQAGIIHLNSEVEGASMIAEGTIIAHIYPSLAEIKKVKVTAYVSSKDVASLSEGDVIHFSAQASQAGQIRLTSTITSIAT
SATKTEAGNFFKIEAETDLSKTFAEKIRYGLEGKFVVITGEKTYFQYIVDEFLGKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=91158 L6419_RS00375 WP_336512672.1 59039..60409(+) (comB) [Streptococcus ruminantium strain GUT-184]
ATGATGGAACATCAGCTATTAGAGAGTGGGGAATTTTACCATCGGCGTTATCATAATGCGGCAAGTAGAGTTATATTGCC
AAGTTTTGCTTTATTAGTCTTTTTGATGATGTTTGCCTTCTTTGCTAAGAAAGAACTGACGGTAGTGACTCGAGCAACTG
TTGAGCCACTTCATGTTTTATCCAAAATTCAATCCACAAGCAACAATCCTATTAAGATGAATTATTTGAAAGAAAATCAG
GAAGTTGCTGTGGGTGATGTTTTGGTTGAATATCAGTCTTCCAGTGAGCAGATTCAAGAAGAAGGTATTAAGAAAAAAAT
TACTCTGTTAAAGGAGCAATTATCTCAGCTTGAACTGTTGAAAAAGAGTTTAGAATCGGGAGAAAACCAGTTTCCTCAAG
AGGATAAGTATGGTTATTCACAATCCTTTGTTGATTATCGAAATAAATTATTGACATTGGAGAGCAATGTAGAGCAGCAG
AATACCACGATTGCTGCTCAGAATGCAGCTATTAGTCAATCGCAGATGGAATTAGGTAATATAGTCAAAACCAGTCAAAA
GGCATTGTCAGATTATAAGAATCTCAGAATGGCCATTCAATCTGACGCTGAAATTTCTGAGGATAATGCAGGTTATTCAC
TCTATGTGGGATATACAACTCAATTATCTCAAGCAACTGGTATAGCTGAAAAAACAACTCTTAAACAGCAGATGTTAACG
CAGCTAGATAACCAAATTAGTCAATTAGAAAATCAGTTGGCTACTTATCGGGTACAGTATGCTGGGGCGGGAGCTCAACA
AGCCTATGCCACTAATTTAGATAGTCAGTCTGCATCGCTCAAATCCCAATATTTGACCAAGGTCGCCCAAGAGTGGACTT
CTCTAACAAGTCAATTAGGTGAACTTGAAGGGACATTGGGGTTACAAGAAAATATGAGAGCTAAGACAAAGATTGTAGCC
AATCAAGCAGGAATTATTCATCTAAATAGTGAAGTTGAGGGAGCATCTATGATTGCAGAAGGTACGATCATTGCTCACAT
TTATCCGAGTTTGGCTGAGATTAAAAAGGTAAAAGTTACCGCCTATGTATCCTCGAAAGATGTTGCCAGCCTGTCTGAGG
GAGATGTGATTCATTTTTCTGCTCAAGCTAGTCAAGCAGGACAGATTCGCCTGACTTCTACCATCACTTCTATTGCAACC
AGTGCGACCAAGACAGAAGCAGGAAATTTCTTTAAGATTGAAGCGGAGACAGACTTATCAAAAACATTTGCTGAGAAAAT
ACGGTATGGATTAGAAGGGAAATTTGTGGTAATTACAGGGGAGAAGACTTATTTTCAGTATATTGTAGATGAATTTTTAG
GGAAAAAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(318-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

52.434

99.123

0.52
  comB Streptococcus pneumoniae Rx1

49.67

99.781

0.496
  comB Streptococcus pneumoniae D39

49.67

99.781

0.496
  comB Streptococcus pneumoniae R6

49.67

99.781

0.496
  comB Streptococcus pneumoniae TIGR4

49.451

99.781

0.493
  comB Streptococcus mitis SK321

49.451

99.781

0.493
  comB Streptococcus mitis NCTC 12261

49.451

99.781

0.493

Multiple sequence alignment