Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   L6419_RS00390 Genome accession   NZ_AP025332
Coordinates   62736..63635 (+) Length   299 a.a.
NCBI ID   WP_024532318.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57736..68635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS00375 (GUT184_00550) comB 59039..60409 (+) 1371 WP_336512672.1 bacteriocin secretion accessory protein Regulator
  L6419_RS00380 (GUT184_00560) ruvB 60840..61838 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  L6419_RS00385 (GUT184_00570) - 62010..62633 (+) 624 WP_237375766.1 HAD-IA family hydrolase -
  L6419_RS00390 (GUT184_00580) comR 62736..63635 (+) 900 WP_024532318.1 helix-turn-helix domain-containing protein Regulator
  L6419_RS00395 (GUT184_00590) - 63851..65077 (+) 1227 WP_237374189.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  L6419_RS00400 (GUT184_00600) - 65279..66778 (+) 1500 WP_155969328.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35655.74 Da        Isoelectric Point: 4.4700

>NTDB_id=91159 L6419_RS00390 WP_024532318.1 62736..63635(+) (comR) [Streptococcus ruminantium strain GUT-184]
MDNKEFGQRVRQLREQAMITREQFCDDEMELSVRQLTRIEAGTCKPTFSKINFIADRLGMGLYELMPDYIKLPERYSKLK
FDVLRTPTYGNEGLVETRNEMITEIYEEYYDDLPEEEQIAMDAFQSIIDVFETKSTQYGREILDDYFEQVYRKEKYTIND
LLILRLYLEHIRFEETSSQMFQIFLDMVKHFPNQTEAIDPGDLFIFRDIMLTSIGILGTKEQFGYIPVLFDTLDKLMMST
QDFQKKPILNLLKWKYELRIHGNKERAREFYEEAVLFAKMIASPHLAEKLEEEWANDSQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=91159 L6419_RS00390 WP_024532318.1 62736..63635(+) (comR) [Streptococcus ruminantium strain GUT-184]
ATGGATAATAAGGAATTTGGTCAGCGTGTACGGCAACTACGAGAACAAGCAATGATAACACGAGAACAGTTTTGTGATGA
TGAAATGGAACTCTCTGTTCGTCAGTTAACTCGGATTGAGGCTGGTACCTGTAAACCAACATTTTCTAAGATAAATTTTA
TCGCTGATCGTTTGGGGATGGGTCTATATGAACTAATGCCAGATTACATCAAACTACCAGAGAGATATTCAAAATTGAAA
TTTGATGTTCTGCGAACGCCTACATATGGGAATGAGGGATTGGTAGAAACACGTAACGAAATGATCACGGAAATTTATGA
AGAGTATTATGATGACTTGCCAGAAGAAGAACAAATAGCAATGGATGCTTTTCAATCCATTATTGACGTGTTTGAAACTA
AATCTACCCAATATGGTCGTGAAATATTGGATGACTATTTTGAACAAGTATATAGAAAAGAAAAATATACCATCAACGAT
TTATTGATTCTTAGGCTATACCTTGAGCACATAAGGTTCGAGGAAACCTCATCGCAAATGTTTCAGATTTTTTTGGATAT
GGTTAAGCATTTTCCAAATCAAACGGAAGCTATAGATCCGGGTGATTTATTCATATTCCGAGATATTATGCTTACTTCAA
TAGGGATATTAGGAACAAAAGAGCAATTTGGCTATATCCCTGTGTTATTTGATACACTGGATAAACTGATGATGTCTACT
CAAGATTTCCAAAAGAAACCAATTTTGAATCTTCTTAAGTGGAAATATGAACTGCGTATTCATGGGAATAAAGAACGTGC
ACGTGAGTTTTATGAAGAAGCAGTTCTGTTTGCGAAAATGATTGCAAGTCCTCATTTGGCTGAAAAATTAGAGGAGGAGT
GGGCTAACGATAGTCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

60.87

100

0.609
  comR Streptococcus suis 05ZYH33

60.87

100

0.609
  comR Streptococcus suis D9

58.472

100

0.589
  comR Streptococcus mutans UA159

38.127

100

0.381
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.31

96.99

0.381
  comR Streptococcus pyogenes MGAS8232

37.288

98.662

0.368

Multiple sequence alignment