Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   U0449_RS02805 Genome accession   NZ_CP139862
Coordinates   555057..556700 (+) Length   547 a.a.
NCBI ID   WP_078136507.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 550057..561700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS02765 - 550528..550911 (-) 384 WP_016398494.1 hypothetical protein -
  U0449_RS02770 - 551540..551872 (-) 333 WP_224757293.1 immunity protein -
  U0449_RS02775 - 552392..552511 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  U0449_RS02780 cipB 552615..552764 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  U0449_RS02785 blpK 553008..553256 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  U0449_RS02790 blpJ 553325..553594 (-) 270 WP_044791635.1 bacteriocin-like peptide BlpJ -
  U0449_RS02795 blpI 554071..554268 (-) 198 WP_001093266.1 bacteriocin-like peptide BlpI -
  U0449_RS02800 comA/nlmT 554543..555130 (+) 588 WP_050218844.1 cysteine peptidase family C39 domain-containing protein Regulator
  U0449_RS02805 comA/nlmT 555057..556700 (+) 1644 WP_078136507.1 peptide cleavage/export ABC transporter Regulator
  U0449_RS02810 - 556711..558072 (+) 1362 WP_001069075.1 bacteriocin secretion accessory protein -
  U0449_RS02815 blpC 558129..558257 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  U0449_RS02820 - 558328..559668 (-) 1341 WP_001017646.1 sensor histidine kinase -
  U0449_RS02825 comE/blpR 559682..560419 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  U0449_RS02830 - 560433..560762 (-) 330 WP_050218846.1 LytTR family DNA-binding domain-containing protein -
  U0449_RS02835 - 561039..561368 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61625.60 Da        Isoelectric Point: 6.5088

>NTDB_id=911466 U0449_RS02805 WP_078136507.1 555057..556700(+) (comA/nlmT) [Streptococcus pneumoniae strain 05H0020-2]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=911466 U0449_RS02805 WP_078136507.1 555057..556700(+) (comA/nlmT) [Streptococcus pneumoniae strain 05H0020-2]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
CCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTCTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTTGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.26

99.817

0.731
  comA Streptococcus mitis NCTC 12261

68.007

100

0.68
  comA Streptococcus pneumoniae D39

67.642

100

0.676
  comA Streptococcus pneumoniae R6

67.642

100

0.676
  comA Streptococcus pneumoniae Rx1

67.642

100

0.676
  comA Streptococcus gordonii str. Challis substr. CH1

67.336

100

0.675
  comA Streptococcus mitis SK321

67.459

100

0.675
  comA Streptococcus pneumoniae TIGR4

67.276

100

0.673