Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   U0449_RS02800 Genome accession   NZ_CP139862
Coordinates   554543..555130 (+) Length   195 a.a.
NCBI ID   WP_050218844.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 549543..560130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS02760 - 549787..550476 (-) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  U0449_RS02765 - 550528..550911 (-) 384 WP_016398494.1 hypothetical protein -
  U0449_RS02770 - 551540..551872 (-) 333 WP_224757293.1 immunity protein -
  U0449_RS02775 - 552392..552511 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  U0449_RS02780 cipB 552615..552764 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  U0449_RS02785 blpK 553008..553256 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  U0449_RS02790 blpJ 553325..553594 (-) 270 WP_044791635.1 bacteriocin-like peptide BlpJ -
  U0449_RS02795 blpI 554071..554268 (-) 198 WP_001093266.1 bacteriocin-like peptide BlpI -
  U0449_RS02800 comA/nlmT 554543..555130 (+) 588 WP_050218844.1 cysteine peptidase family C39 domain-containing protein Regulator
  U0449_RS02805 comA/nlmT 555057..556700 (+) 1644 WP_078136507.1 peptide cleavage/export ABC transporter Regulator
  U0449_RS02810 - 556711..558072 (+) 1362 WP_001069075.1 bacteriocin secretion accessory protein -
  U0449_RS02815 blpC 558129..558257 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  U0449_RS02820 - 558328..559668 (-) 1341 WP_001017646.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22252.65 Da        Isoelectric Point: 9.5174

>NTDB_id=911465 U0449_RS02800 WP_050218844.1 554543..555130(+) (comA/nlmT) [Streptococcus pneumoniae strain 05H0020-2]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEEKLQHYYVVYQTKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=911465 U0449_RS02800 WP_050218844.1 554543..555130(+) (comA/nlmT) [Streptococcus pneumoniae strain 05H0020-2]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGAAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGGTTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.348

94.359

0.513
  comA Streptococcus mitis SK321

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.261

94.359

0.503
  comA Streptococcus pneumoniae D39

53.261

94.359

0.503
  comA Streptococcus pneumoniae R6

53.261

94.359

0.503
  comA Streptococcus pneumoniae TIGR4

53.261

94.359

0.503
  comA Streptococcus gordonii str. Challis substr. CH1

52.174

94.359

0.492