Detailed information NTG0091112

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: SUT_RS00790
• Genome accession: NZ_AP025331
• Coordinates: 124765..125715 (+)
• Length: 316 a.a.
• NCBI ID: WP_155962599.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-183
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119765..130715

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUT_RS00780 (GUT183_01250)	-	123248..123616 (+)	369	WP_156019557.1	DUF1033 family protein	-
SUT_RS00785 (GUT183_01260)	-	123654..124604 (-)	951	WP_024532257.1	S66 family peptidase	-
SUT_RS00790 (GUT183_01270)	comYA	124765..125715 (+)	951	WP_155962599.1	competence type IV pilus ATPase ComGA	Machinery gene
SUT_RS00795 (GUT183_01280)	comYB	125636..126667 (+)	1032	WP_155962598.1	competence type IV pilus assembly protein ComGB	Machinery gene
SUT_RS00800 (GUT183_01290)	-	126732..128186 (-)	1455	WP_237373309.1	recombinase family protein	-
SUT_RS00805 (GUT183_01300)	-	128314..128982 (-)	669	WP_237373311.1	NYN domain-containing protein	-
SUT_RS00810 (GUT183_01310)	-	129146..129928 (-)	783	WP_237373313.1	XRE family transcriptional regulator	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 35633.60 Da
• Isoelectric Point: 6.6183

>NTDB_id=91112 SUT_RS00790 WP_155962599.1 124765..125715(+) (comYA) [Streptococcus ruminantium strain GUT-183]
MIQEKARQMVEQAVLARVSDLYLVPRGESYQLYHRIMDERVFLQELNEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYN
YGSGQISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERIAREIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSTEELNNALQGIAYQRLIGGGGVVDFAKENFQNHSADQWNKQIDSLFAAGYISHRQAETEKIVFGSPA

Nucleotide

• Length: 951 bp

>NTDB_id=91112 SUT_RS00790 WP_155962599.1 124765..125715(+) (comYA) [Streptococcus ruminantium strain GUT-183]
ATGATTCAAGAAAAAGCAAGACAGATGGTGGAGCAAGCAGTGCTTGCTAGGGTTAGCGACCTTTATTTGGTTCCGCGAGG
AGAGTCCTATCAGCTCTATCATCGGATTATGGATGAACGAGTATTTTTGCAGGAATTGAATGAAGAAGAAGTGACAGCCA
TCATCAGTCATTTCAAGTTTTTGGCTGGTTTGAATGTCGGTGAAAAGCGTCGCAGTCAGCAAGGTTCTTGTGATTATAAT
TATGGTTCAGGGCAGATCTCCCTCCGCTTGTCCACTGTTGGTGATTATCGAGGTAAGGAGAGTTTGGTGATTCGATTGCT
GTACGATAACGATAAGGAACTCAAGTTTTGGTTTGAGGCAGCAGAGCGGATTGCTAGGGAAATCAAGGGGCGAGGACTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGCAAAACCACGCTTATGTACCATCTTGCTAGGCTGAAATTCCCAGATAAACAG
ATTTTAACGATTGAAGATCCGGTAGAAATCAAACAGGAAGATATGCTCCAACTTCAGCTCAATGAAGCGATTGGGGCAAC
GTATGACAATCTGATTAAGCTGTCTCTTCGTCATCGGCCGGATCTACTGATTATTGGGGAAATACGAGATGCAGAAACAG
CAAGGGCAGTCATTCGTGCTAGTCTGACAGGTGCAACAGTTTTTTCTACTGTCCATGCTCGCAGTATTTCAGGGGTCTAT
GCTCGGATGCTAGAGCTGGGTGTCAGTACAGAGGAGTTAAATAATGCCCTTCAAGGAATTGCCTATCAACGTTTGATTGG
GGGAGGGGGTGTTGTAGATTTTGCCAAAGAAAACTTCCAAAACCATTCTGCTGACCAGTGGAATAAACAGATTGATAGCC
TTTTTGCAGCAGGATATATCAGTCATAGACAGGCAGAGACAGAAAAAATTGTCTTTGGATCACCAGCGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus gordonii str. Challis substr. CH1	67.742	98.101	0.665
comYA	Streptococcus mutans UA159	67.524	98.418	0.665
comYA	Streptococcus mutans UA140	67.524	98.418	0.665
comGA/cglA/cilD	Streptococcus pneumoniae D39	63.782	98.734	0.63
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	63.782	98.734	0.63
comGA/cglA/cilD	Streptococcus pneumoniae R6	63.782	98.734	0.63
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	63.782	98.734	0.63
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	63.462	98.734	0.627
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	63.871	98.101	0.627
comGA	Lactococcus lactis subsp. cremoris KW2	54.019	98.418	0.532
comGA	Latilactobacillus sakei subsp. sakei 23K	42.599	87.658	0.373