Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SUT_RS00425 Genome accession   NZ_AP025331
Coordinates   70318..71499 (+) Length   393 a.a.
NCBI ID   WP_237373299.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 65318..76499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS00405 (GUT183_00620) - 65462..66961 (+) 1500 WP_237373296.1 quinol oxidase -
  SUT_RS00410 (GUT183_00630) mutL 67099..69036 (+) 1938 WP_237373297.1 DNA mismatch repair endonuclease MutL -
  SUT_RS00415 (GUT183_00640) ruvA 69065..69655 (+) 591 WP_237373298.1 Holliday junction branch migration protein RuvA -
  SUT_RS00420 (GUT183_00650) - 69705..70259 (+) 555 WP_024532323.1 DNA-3-methyladenine glycosylase I -
  SUT_RS00425 (GUT183_00660) cinA 70318..71499 (+) 1182 WP_237373299.1 competence/damage-inducible protein A Machinery gene
  SUT_RS00430 (GUT183_00670) recA 71551..72693 (+) 1143 WP_024532325.1 recombinase RecA Machinery gene
  SUT_RS00435 (GUT183_00680) spx 73223..73621 (+) 399 WP_024532326.1 transcriptional regulator Spx -
  SUT_RS00440 (GUT183_00690) - 73725..73991 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  SUT_RS00445 (GUT183_00700) ruvX 73991..74410 (+) 420 WP_032537883.1 Holliday junction resolvase RuvX -
  SUT_RS00450 (GUT183_00710) - 74422..74727 (+) 306 WP_024532328.1 DUF1292 domain-containing protein -
  SUT_RS00455 (GUT183_00720) - 75102..75647 (+) 546 WP_336512694.1 nucleotidyltransferase family protein -
  SUT_RS00460 (GUT183_00730) comX/sigX 75740..76210 (+) 471 WP_024532329.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42503.59 Da        Isoelectric Point: 4.8094

>NTDB_id=91106 SUT_RS00425 WP_237373299.1 70318..71499(+) (cinA) [Streptococcus ruminantium strain GUT-183]
MKAELIAVGTEILTGQIVNTNTQFLSEKCAELGIDVYFHTSVGDNQGRLLQVLDIASRRSDLVILCGGLGPTEDDLTKQT
LARFLGKELVLDEQAKLKLDRFFASRPGRIRTPNNERQAQIVAGSTPLQNPAGLAVGGLIEQEGITYVVLPGPPSELKAM
FTTSLLPMLDNSHSQLYSRVLRFFGIGESQLVTILADLIDNQTNPTLAPYAKVGEVTLRLSTKATCQEEADQVLNRLETQ
ILQRDKLAEYFYAYGEENSLVKLVATSLAGKEQTLAVWEQGTGGLLQAELSLALAEQPYFIGGRVVGQKGAASGNLSVQA
SGIRDDLQADLGLAMSVFIKPSSTVDNVLAKVSLALSSPSGVIQKELDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=91106 SUT_RS00425 WP_237373299.1 70318..71499(+) (cinA) [Streptococcus ruminantium strain GUT-183]
ATGAAAGCAGAACTAATCGCTGTTGGAACGGAGATTTTAACAGGGCAGATTGTTAATACGAATACTCAGTTTCTATCCGA
AAAATGTGCAGAGCTGGGAATTGATGTCTACTTCCACACAAGTGTTGGAGACAACCAAGGTAGACTTTTACAGGTGCTGG
ATATAGCCAGTAGACGCAGTGATTTGGTCATTCTATGTGGAGGTCTTGGCCCTACGGAAGATGATTTAACCAAACAAACA
TTAGCTCGATTTTTAGGGAAAGAATTAGTTTTGGATGAGCAGGCCAAGCTTAAATTAGACCGTTTTTTTGCTAGTCGTCC
AGGTCGTATTCGCACACCTAACAATGAACGTCAGGCACAGATTGTAGCAGGAAGTACCCCCTTGCAAAATCCTGCTGGTT
TAGCCGTTGGGGGATTGATTGAGCAAGAAGGAATAACCTATGTTGTACTTCCAGGCCCTCCGAGTGAGCTAAAAGCTATG
TTTACTACCAGTCTATTGCCGATGCTAGACAATTCTCATAGCCAACTTTACTCACGGGTTCTGAGATTTTTTGGTATTGG
AGAAAGTCAGCTGGTGACGATTTTAGCAGATTTGATTGATAATCAGACTAATCCAACTTTAGCACCTTATGCTAAAGTCG
GTGAAGTCACCTTGCGCCTGTCTACCAAAGCTACTTGCCAAGAAGAAGCAGATCAAGTATTGAATCGTTTAGAAACACAA
ATTTTGCAACGTGATAAACTAGCAGAGTATTTCTATGCCTATGGTGAGGAAAATAGTCTGGTGAAATTGGTGGCGACCAG
CTTGGCGGGGAAAGAGCAAACTCTGGCTGTATGGGAACAGGGGACGGGTGGGCTCTTACAAGCAGAATTGAGTTTGGCGC
TGGCCGAACAGCCTTATTTTATCGGAGGTAGGGTTGTTGGTCAGAAAGGAGCTGCTTCGGGCAATTTGTCTGTTCAAGCA
AGCGGTATTCGTGACGATCTACAAGCCGATTTAGGTTTAGCTATGTCGGTTTTTATCAAGCCGTCCTCAACGGTAGACAA
CGTTCTTGCCAAGGTCTCACTGGCCTTATCAAGTCCTTCTGGAGTTATTCAAAAGGAGCTAGATTTGGGAGGTTATTCAT
GGCAACATATCCGTCAACTAGCTTGTTTACAAGCTCTAGATTTTGTACGAAATACTTTGTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(309-393)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

79.135

100

0.791
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

54.808

100

0.58
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Streptococcus pneumoniae TIGR4

54.327

100

0.575
  cinA Streptococcus pneumoniae Rx1

54.327

100

0.575
  cinA Streptococcus pneumoniae R6

54.327

100

0.575
  cinA Streptococcus pneumoniae D39

54.087

100

0.573
  cinA Bacillus subtilis subsp. subtilis str. 168

48.208

78.117

0.377

Multiple sequence alignment