Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SHT65_RS14450 Genome accession   NZ_CP138641
Coordinates   2961023..2962267 (-) Length   414 a.a.
NCBI ID   WP_010820333.1    Uniprot ID   -
Organism   Enterococcus faecalis strain ES-90-2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2956023..2967267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SHT65_RS14430 (SHT65_14430) - 2956493..2956879 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  SHT65_RS14435 (SHT65_14435) - 2956953..2957750 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  SHT65_RS14440 (SHT65_14440) rny 2957910..2959466 (-) 1557 WP_002354863.1 ribonuclease Y -
  SHT65_RS14445 (SHT65_14445) recA 2959863..2960909 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  SHT65_RS14450 (SHT65_14450) cinA 2961023..2962267 (-) 1245 WP_010820333.1 competence/damage-inducible protein A Machinery gene
  SHT65_RS14455 (SHT65_14455) - 2962458..2963663 (+) 1206 WP_002359001.1 hypothetical protein -
  SHT65_RS14460 (SHT65_14460) - 2963739..2964368 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  SHT65_RS14465 (SHT65_14465) - 2964427..2964852 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  SHT65_RS14470 (SHT65_14470) - 2964941..2965324 (-) 384 WP_002354850.1 YccF domain-containing protein -
  SHT65_RS14475 (SHT65_14475) - 2965488..2966279 (+) 792 WP_010820334.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45221.34 Da        Isoelectric Point: 4.6698

>NTDB_id=903961 SHT65_RS14450 WP_010820333.1 2961023..2962267(-) (cinA) [Enterococcus faecalis strain ES-90-2]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVVECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=903961 SHT65_RS14450 WP_010820333.1 2961023..2962267(-) (cinA) [Enterococcus faecalis strain ES-90-2]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCTATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACTGTTGTAGAATGTTTCCATTTTAACCGTGATCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437