Detailed information NTG0898213

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: R5U37_RS11515
• Genome accession: NZ_CP137476
• Coordinates: 2325054..2326295 (-)
• Length: 413 a.a.
• NCBI ID: WP_002298209.1
• Uniprot ID: -
• Organism: Enterococcus faecium strain HMC8C-1
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2326354..2327262	2325054..2326295	flank	59

Gene organization within MGE regions

Location: 2325054..2327262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R5U37_RS11515 (R5U37_11535)	cinA	2325054..2326295 (-)	1242	WP_002298209.1	competence/damage-inducible protein A	Machinery gene
R5U37_RS11520 (R5U37_11540)	-	2326354..2327262 (-)	909	WP_061573572.1	IS982-like element ISEfm1 family transposase	-

Sequence

Protein

• Length: 413 a.a.
• Molecular weight: 45457.84 Da
• Isoelectric Point: 4.6507

>NTDB_id=898213 R5U37_RS11515 WP_002298209.1 2325054..2326295(-) (cinA) [Enterococcus faecium strain HMC8C-1]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLVYFETTHRKMTKNNLQQSQIIEGGIPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide

• Length: 1242 bp

>NTDB_id=898213 R5U37_RS11515 WP_002298209.1 2325054..2326295(-) (cinA) [Enterococcus faecium strain HMC8C-1]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGTATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATCATCGAAGGCGGGATTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAAACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (180-253)

• Competence-damaged protein (CinA) (258-410)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mitis SK321	51.429	100	0.523
cinA	Streptococcus pneumoniae TIGR4	51.19	100	0.521
cinA	Streptococcus mitis NCTC 12261	51.19	100	0.521
cinA	Streptococcus mutans UA159	51.566	100	0.518
cinA	Streptococcus pneumoniae R6	50.952	100	0.518
cinA	Streptococcus pneumoniae Rx1	50.952	100	0.518
cinA	Streptococcus pneumoniae D39	50.952	100	0.518
cinA	Bacillus subtilis subsp. subtilis str. 168	47.573	99.758	0.475
cinA	Streptococcus suis isolate S10	41.787	100	0.419