Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4702_RS02685 Genome accession   NZ_CP137106
Coordinates   537245..538888 (+) Length   547 a.a.
NCBI ID   WP_078138292.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P4028     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 532245..543888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS02645 - 532875..533108 (-) 234 WP_033705506.1 bacteriocin class II family protein -
  R4702_RS02650 - 533355..534324 (-) 970 Protein_528 thioredoxin domain-containing protein -
  R4702_RS02655 - 534485..534856 (-) 372 WP_033705507.1 hypothetical protein -
  R4702_RS02660 - 535324..535443 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R4702_RS10965 - 535446..535511 (-) 66 Protein_531 ComC/BlpC family peptide pheromone/bacteriocin -
  R4702_RS02665 cipB 535547..535696 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R4702_RS02670 blpN 535940..536143 (-) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  R4702_RS02675 blpM 536159..536413 (-) 255 WP_317810210.1 two-peptide bacteriocin subunit BlpM -
  R4702_RS02680 comA/nlmT 536731..537318 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4702_RS02685 comA/nlmT 537245..538888 (+) 1644 WP_078138292.1 peptide cleavage/export ABC transporter Regulator
  R4702_RS02690 - 538899..540260 (+) 1362 WP_024478409.1 bacteriocin secretion accessory protein -
  R4702_RS02695 blpC 540317..540472 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  R4702_RS02700 - 540514..541854 (-) 1341 WP_001017624.1 sensor histidine kinase -
  R4702_RS02705 comE/blpR 541868..542605 (-) 738 WP_001219145.1 response regulator transcription factor Regulator
  R4702_RS02710 - 542610..542948 (-) 339 WP_000682118.1 LytTR family DNA-binding domain-containing protein -
  R4702_RS02715 - 543224..543553 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61615.65 Da        Isoelectric Point: 6.9394

>NTDB_id=895537 R4702_RS02685 WP_078138292.1 537245..538888(+) (comA/nlmT) [Streptococcus pneumoniae strain 16P4028]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIENINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIKVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=895537 R4702_RS02685 WP_078138292.1 537245..538888(+) (comA/nlmT) [Streptococcus pneumoniae strain 16P4028]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAAATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGT
AGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTAAAGTTGGTAGCCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.344

99.817

0.722
  comA Streptococcus mitis NCTC 12261

66.91

100

0.669
  comA Streptococcus pneumoniae D39

66.545

100

0.665
  comA Streptococcus pneumoniae R6

66.545

100

0.665
  comA Streptococcus pneumoniae Rx1

66.545

100

0.665
  comA Streptococcus gordonii str. Challis substr. CH1

66.241

100

0.664
  comA Streptococcus mitis SK321

66.362

100

0.664
  comA Streptococcus pneumoniae TIGR4

66.179

100

0.662