Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R4702_RS02705 Genome accession   NZ_CP137106
Coordinates   541868..542605 (-) Length   245 a.a.
NCBI ID   WP_001219145.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P4028     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 536868..547605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS02685 comA/nlmT 537245..538888 (+) 1644 WP_078138292.1 peptide cleavage/export ABC transporter Regulator
  R4702_RS02690 - 538899..540260 (+) 1362 WP_024478409.1 bacteriocin secretion accessory protein -
  R4702_RS02695 blpC 540317..540472 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  R4702_RS02700 - 540514..541854 (-) 1341 WP_001017624.1 sensor histidine kinase -
  R4702_RS02705 comE/blpR 541868..542605 (-) 738 WP_001219145.1 response regulator transcription factor Regulator
  R4702_RS02710 - 542610..542948 (-) 339 WP_000682118.1 LytTR family DNA-binding domain-containing protein -
  R4702_RS02715 - 543224..543553 (+) 330 WP_000132572.1 hypothetical protein -
  R4702_RS02720 - 543721..544770 (-) 1050 WP_317810222.1 ABC transporter permease -
  R4702_RS02725 pptA 544767..545498 (-) 732 WP_000889922.1 ABC transporter ATP-binding protein Regulator
  R4702_RS02730 - 545566..545976 (+) 411 WP_001278304.1 HIT family protein -
  R4702_RS02735 - 545986..546273 (+) 288 WP_317810224.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28798.90 Da        Isoelectric Point: 6.0454

>NTDB_id=895538 R4702_RS02705 WP_001219145.1 541868..542605(-) (comE/blpR) [Streptococcus pneumoniae strain 16P4028]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=895538 R4702_RS02705 WP_001219145.1 541868..542605(-) (comE/blpR) [Streptococcus pneumoniae strain 16P4028]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCCCAGCTCTTTTGAGGTATTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGGCTGGAAGTGGCTAGAAAGATTCGGGAACAAGAC
CCCTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGAATCGAGACAGCTCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACATCCCCAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGTTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.321

99.184

0.539
  comE/comE1 Streptococcus equinus JB1

43.882

96.735

0.424
  comE/comE2 Streptococcus equinus JB1

38.843

98.776

0.384
  comE Streptococcus infantis strain Atu-4

36.179

100

0.363