Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   RX143_RS12420 Genome accession   NZ_CP136360
Coordinates   2592138..2593382 (-) Length   414 a.a.
NCBI ID   WP_010819079.1    Uniprot ID   -
Organism   Enterococcus faecalis strain ES-3222     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2587138..2598382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RX143_RS12395 (RX143_12395) - 2587608..2587994 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  RX143_RS12400 (RX143_12400) - 2588068..2588865 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  RX143_RS12405 (RX143_12405) rny 2589025..2590581 (-) 1557 WP_002354863.1 ribonuclease Y -
  RX143_RS12410 (RX143_12410) - 2590777..2590872 (-) 96 WP_104854405.1 transcriptional antiterminator -
  RX143_RS12415 (RX143_12415) recA 2590978..2592024 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  RX143_RS12420 (RX143_12420) cinA 2592138..2593382 (-) 1245 WP_010819079.1 competence/damage-inducible protein A Machinery gene
  RX143_RS12425 (RX143_12425) - 2593574..2594779 (+) 1206 WP_010819080.1 hypothetical protein -
  RX143_RS12430 (RX143_12430) - 2595005..2595109 (-) 105 Protein_2423 type II toxin-antitoxin system RelE/ParE family toxin -
  RX143_RS13210 - 2595112..2595216 (-) 105 Protein_2424 antitoxin -
  RX143_RS12435 (RX143_12435) - 2595839..2596102 (-) 264 WP_002396818.1 hypothetical protein -
  RX143_RS12440 (RX143_12440) - 2596106..2598235 (-) 2130 WP_002424924.1 peptidase domain-containing ABC transporter -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45226.32 Da        Isoelectric Point: 4.7172

>NTDB_id=890335 RX143_RS12420 WP_010819079.1 2592138..2593382(-) (cinA) [Enterococcus faecalis strain ES-3222]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVFCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=890335 RX143_RS12420 WP_010819079.1 2592138..2593382(-) (cinA) [Enterococcus faecalis strain ES-3222]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCTTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTAATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.153

100

0.527
  cinA Streptococcus mitis SK321

51.3

100

0.524
  cinA Streptococcus mitis NCTC 12261

51.064

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

49.882

100

0.51
  cinA Streptococcus pneumoniae R6

49.882

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.768

98.068

0.478
  cinA Streptococcus suis isolate S10

43.796

99.275

0.435