Detailed information NTG0888990

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: F6I35_RS10735
• Genome accession: NZ_CP136160
• Coordinates: 2030857..2032047 (+)
• Length: 396 a.a.
• NCBI ID: WP_024052475.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain UMB8616
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2025857..2037047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I35_RS10710 (F6I35_0010705)	comE	2027664..2028413 (-)	750	WP_024052478.1	competence system response regulator transcription factor ComE	Regulator
F6I35_RS10715 (F6I35_0010710)	comD/comD2	2028413..2029735 (-)	1323	WP_371317911.1	sensor histidine kinase	Regulator
F6I35_RS10720 (F6I35_0010715)	-	2029756..2029902 (-)	147	WP_003029519.1	bacteriocin	-
F6I35_RS10730 (F6I35_0010725)	rlmH	2030184..2030663 (-)	480	WP_024052476.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
F6I35_RS10735 (F6I35_0010730)	htrA	2030857..2032047 (+)	1191	WP_024052475.1	S1C family serine protease	Regulator
F6I35_RS10740 (F6I35_0010735)	spo0J	2032102..2032869 (+)	768	WP_070672281.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41711.71 Da
• Isoelectric Point: 9.4264

>NTDB_id=888990 F6I35_RS10735 WP_024052475.1 2030857..2032047(+) (htrA) [Streptococcus anginosus strain UMB8616]
MKNSSNFTKKLLLLFMVLAIGFIGGLLGNLTSSKLSTNSSTTTKVNQVTTAYKNTNSTTQAVSKVKDAVVSVITYANNNS
QNSVFGNDDSNNNNDNSQQVASEGSGVIYKKDGKYAYLVTNTHVISGAKKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ADKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDVINIINQLEANGTVTRPALGIQMIDITNLSSSDLSRLKLPSKITSGV
VVRSAQSGMPAEGKLQKYDVITKVDDKEIFSTSDLQSALYKHSIGDNIKITFYRDGKETTTTIKLTKSTKDLDSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=888990 F6I35_RS10735 WP_024052475.1 2030857..2032047(+) (htrA) [Streptococcus anginosus strain UMB8616]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTGTTATTGCTTTTCATGGTCTTAGCTATAGGTTTTATCGGTGGTTTACT
TGGAAACTTAACTTCATCTAAATTATCAACAAATAGCTCTACAACGACTAAAGTTAATCAAGTTACTACTGCTTATAAAA
ATACAAATTCCACAACACAAGCTGTGAGTAAAGTGAAAGATGCTGTGGTATCCGTTATTACCTATGCTAATAATAATTCA
CAAAACAGCGTGTTTGGAAATGATGATTCAAATAATAACAATGATAATTCTCAACAAGTAGCTAGCGAAGGATCTGGGGT
TATTTATAAAAAAGATGGAAAATACGCTTACTTAGTAACCAATACTCACGTTATCAGTGGTGCTAAAAAAGTTGACATTC
GTTTAGCAGATGGTAATAAAGTTCCTGGAGAAATTGTAGGGTCAGATACTTATTCTGATATCTCCGTTGTTCGAATTAGT
GCTGATAAAGTAAAATCAGTTGCTGAATTTGGAGATTCTAGTAAATTGACGGTTGGTGAGACAGCTATTGCGATTGGAAG
TCCGCTCGGTTCAAATTACGCTAACACTGTGACGCAAGGAATTATTTCTAGTTTAAATCGTAATGTTTCTTTAAAATCTG
AAGACGGACAAACGATTTCAACACAAGCTATTCAAACAGACACAGCTATTAACCCAGGGAACTCTGGTGGACCACTTGTG
AATATCCAAGGACAAGTAATTGGTATTACTTCAAGTAAAATAGCTAGCAACGGCGGAACTTCGGTTGAAGGATTAGGATT
TGCTATTCCATCTAATGATGTTATAAACATTATTAACCAGTTAGAAGCAAATGGAACTGTTACACGACCAGCTCTAGGAA
TCCAAATGATTGACATCACTAATCTGTCTAGTTCAGATCTATCACGCTTAAAACTTCCATCAAAAATAACTAGTGGAGTT
GTCGTACGTTCAGCTCAATCTGGAATGCCAGCTGAAGGAAAACTTCAAAAATATGATGTGATTACAAAAGTAGATGATAA
AGAAATTTTTTCAACAAGTGATTTACAATCCGCTTTATACAAACATTCAATTGGTGACAACATAAAAATCACTTTCTATC
GTGATGGAAAAGAAACTACTACTACCATTAAGCTTACAAAATCTACAAAAGATTTAGATTCAAATAATTGA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• PDZ domain (PDZ_2) (290-385)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	75.312	100	0.763
htrA	Streptococcus mitis NCTC 12261	72.544	100	0.727
htrA	Streptococcus pneumoniae Rx1	72.292	100	0.725
htrA	Streptococcus pneumoniae D39	72.292	100	0.725
htrA	Streptococcus pneumoniae R6	72.292	100	0.725
htrA	Streptococcus pneumoniae TIGR4	72.292	100	0.725
htrA	Streptococcus mutans UA159	55.471	99.242	0.551