Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   F6I35_RS10715 Genome accession   NZ_CP136160
Coordinates   2028413..2029735 (-) Length   440 a.a.
NCBI ID   WP_371317911.1    Uniprot ID   -
Organism   Streptococcus anginosus strain UMB8616     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023413..2034735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS10695 (F6I35_0010690) - 2024740..2027316 (+) 2577 WP_024052479.1 YfhO family protein -
  F6I35_RS10710 (F6I35_0010705) comE 2027664..2028413 (-) 750 WP_024052478.1 competence system response regulator transcription factor ComE Regulator
  F6I35_RS10715 (F6I35_0010710) comD/comD2 2028413..2029735 (-) 1323 WP_371317911.1 sensor histidine kinase Regulator
  F6I35_RS10720 (F6I35_0010715) - 2029756..2029902 (-) 147 WP_003029519.1 bacteriocin -
  F6I35_RS10730 (F6I35_0010725) rlmH 2030184..2030663 (-) 480 WP_024052476.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  F6I35_RS10735 (F6I35_0010730) htrA 2030857..2032047 (+) 1191 WP_024052475.1 S1C family serine protease Regulator
  F6I35_RS10740 (F6I35_0010735) spo0J 2032102..2032869 (+) 768 WP_070672281.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51970.67 Da        Isoelectric Point: 8.7195

>NTDB_id=888989 F6I35_RS10715 WP_371317911.1 2028413..2029735(-) (comD/comD2) [Streptococcus anginosus strain UMB8616]
MKIEFVHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDLTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVR
RHLSVFLALFLSLVVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLIFILKAIDYFKFNFKYFKKADFKENILQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVIRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=888989 F6I35_RS10715 WP_371317911.1 2028413..2029735(-) (comD/comD2) [Streptococcus anginosus strain UMB8616]
GTGAAAATAGAATTTGTACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTAACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAGA
AGACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGTTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTCAAAGAGAATATTTTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTATCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGTGAAAAGTATGAAA
AAGAAGAACAAATTAAACAAAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTATAAT
GAAATTCGAGGTTTTCGTCATGATTATGGAGGAATGTTGGCAAGCTTCCAATCAGCCATTCATACAGGTGATATAAAAGA
AGTAGAGCGAATTTATCAGGAAGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTTAAACCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGCGTCCTTTTGAATAA
TGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATAAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.543
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

59.162

86.818

0.514
  comD/comD2 Streptococcus pneumoniae TIGR4

48.404

85.455

0.414
  comD Streptococcus mitis NCTC 12261

48.404

85.455

0.414
  comD Streptococcus mitis SK321

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae Rx1

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae D39

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae R6

47.872

85.455

0.409