Detailed information NTG0880303

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: RJW53_RS00785
• Genome accession: NZ_CP134488
• Coordinates: 123994..125031 (+)
• Length: 345 a.a.
• NCBI ID: WP_257116212.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NLS50
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118994..130031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW53_RS00770 (RJW53_00770)	-	121696..122061 (+)	366	WP_023369079.1	DUF1033 family protein	-
RJW53_RS00775 (RJW53_00775)	-	122096..123046 (-)	951	Protein_119	S66 peptidase family protein	-
RJW53_RS00780 (RJW53_00780)	comYA	123132..124082 (+)	951	WP_044760311.1	competence type IV pilus ATPase ComGA	Machinery gene
RJW53_RS00785 (RJW53_00785)	comYB	123994..125031 (+)	1038	WP_257116212.1	competence type IV pilus assembly protein ComGB	Machinery gene
RJW53_RS00790 (RJW53_00790)	comYC	125033..125314 (+)	282	WP_074389246.1	competence type IV pilus major pilin ComGC	Machinery gene
RJW53_RS00795 (RJW53_00795)	comGD	125295..125702 (+)	408	WP_074389247.1	competence type IV pilus minor pilin ComGD	-
RJW53_RS00800 (RJW53_00800)	comYE	125674..125967 (+)	294	WP_024413203.1	competence type IV pilus minor pilin ComGE	Machinery gene
RJW53_RS00805 (RJW53_00805)	comGF/cglF	125954..126388 (+)	435	WP_074389248.1	competence type IV pilus minor pilin ComGF	Machinery gene
RJW53_RS00810 (RJW53_00810)	comGG	126366..126776 (+)	411	WP_074392769.1	competence type IV pilus minor pilin ComGG	-
RJW53_RS00815 (RJW53_00815)	-	127257..127682 (-)	426	WP_226319165.1	ArpU family phage packaging/lysis transcriptional regulator	-
RJW53_RS00820 (RJW53_00820)	-	128006..128581 (-)	576	WP_074392204.1	hypothetical protein	-
RJW53_RS00825 (RJW53_00825)	-	128602..128775 (-)	174	WP_171840772.1	hypothetical protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 38962.96 Da
• Isoelectric Point: 9.1394

>NTDB_id=880303 RJW53_RS00785 WP_257116212.1 123994..125031(+) (comYB) [Streptococcus suis strain NLS50]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVGILAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide

• Length: 1038 bp

>NTDB_id=880303 RJW53_RS00785 WP_257116212.1 123994..125031(+) (comYB) [Streptococcus suis strain NLS50]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCG
CCAGCGTAAGGTTATTGAACTGTTTAACAATCTCTTTGCTAGTGGCTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGTCAACTTTTGGCAGATCCCTATACCCAGGTCTTATCGGATGGCCTTCTTGCAGGAAAGCCGTTTTCAAGCTTATTA
GCGGATTTGCGATTTTCAGATGCAGTTGTCACGCAGGTAGCCTTAGCAGAAGTTCACGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCTTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTAATTGAGGTAGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAATTACCTTCTGCCTCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTGATCAATCATCTACCGACCATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGGGATCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGATTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAAACCTACGCCTTTTTTAAGCGGGAGCTGAGCCTCATCGTGGAGTATGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus gordonii str. Challis substr. CH1	63.743	99.13	0.632
comGB/cglB	Streptococcus mitis NCTC 12261	60.896	97.101	0.591
comYB	Streptococcus mutans UA140	59.531	98.841	0.588
comYB	Streptococcus mutans UA159	59.531	98.841	0.588
comGB/cglB	Streptococcus mitis SK321	60.597	97.101	0.588
comGB/cglB	Streptococcus pneumoniae Rx1	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae D39	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae R6	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae TIGR4	60.299	97.101	0.586
comGB	Lactococcus lactis subsp. cremoris KW2	50.742	97.681	0.496