Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   RJW53_RS00780 Genome accession   NZ_CP134488
Coordinates   123132..124082 (+) Length   316 a.a.
NCBI ID   WP_044760311.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS50     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 118132..129082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS00770 (RJW53_00770) - 121696..122061 (+) 366 WP_023369079.1 DUF1033 family protein -
  RJW53_RS00775 (RJW53_00775) - 122096..123046 (-) 951 Protein_119 S66 peptidase family protein -
  RJW53_RS00780 (RJW53_00780) comYA 123132..124082 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  RJW53_RS00785 (RJW53_00785) comYB 123994..125031 (+) 1038 WP_257116212.1 competence type IV pilus assembly protein ComGB Machinery gene
  RJW53_RS00790 (RJW53_00790) comYC 125033..125314 (+) 282 WP_074389246.1 competence type IV pilus major pilin ComGC Machinery gene
  RJW53_RS00795 (RJW53_00795) comGD 125295..125702 (+) 408 WP_074389247.1 competence type IV pilus minor pilin ComGD -
  RJW53_RS00800 (RJW53_00800) comYE 125674..125967 (+) 294 WP_024413203.1 competence type IV pilus minor pilin ComGE Machinery gene
  RJW53_RS00805 (RJW53_00805) comGF/cglF 125954..126388 (+) 435 WP_074389248.1 competence type IV pilus minor pilin ComGF Machinery gene
  RJW53_RS00810 (RJW53_00810) comGG 126366..126776 (+) 411 WP_074392769.1 competence type IV pilus minor pilin ComGG -
  RJW53_RS00815 (RJW53_00815) - 127257..127682 (-) 426 WP_226319165.1 ArpU family phage packaging/lysis transcriptional regulator -
  RJW53_RS00820 (RJW53_00820) - 128006..128581 (-) 576 WP_074392204.1 hypothetical protein -
  RJW53_RS00825 (RJW53_00825) - 128602..128775 (-) 174 WP_171840772.1 hypothetical protein -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35410.29 Da        Isoelectric Point: 5.4744

>NTDB_id=880302 RJW53_RS00780 WP_044760311.1 123132..124082(+) (comYA) [Streptococcus suis strain NLS50]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGAPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=880302 RJW53_RS00780 WP_044760311.1 123132..124082(+) (comYA) [Streptococcus suis strain NLS50]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGATAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCCCGTATGTTGGAATTGGGTGTCAGCCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGGC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361