Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   Q7580_RS12820 Genome accession   NZ_CP131825
Coordinates   2647731..2648972 (-) Length   413 a.a.
NCBI ID   WP_342252012.1    Uniprot ID   -
Organism   Enterococcus faecium strain 2016C07-254     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2642731..2653972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7580_RS12805 (Q7580_12745) proC 2643721..2644527 (+) 807 WP_002303638.1 pyrroline-5-carboxylate reductase -
  Q7580_RS12810 (Q7580_12750) rny 2644606..2646162 (-) 1557 WP_002287336.1 ribonuclease Y -
  Q7580_RS12815 (Q7580_12755) recA 2646573..2647622 (-) 1050 WP_002287328.1 recombinase RecA Machinery gene
  Q7580_RS12820 (Q7580_12760) cinA 2647731..2648972 (-) 1242 WP_342252012.1 competence/damage-inducible protein A Machinery gene
  Q7580_RS12825 (Q7580_12765) pgsA 2649212..2649790 (-) 579 WP_002296025.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  Q7580_RS12830 (Q7580_12770) - 2649999..2650922 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  Q7580_RS12835 (Q7580_12775) - 2651661..2652947 (-) 1287 WP_002287425.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45357.73 Da        Isoelectric Point: 4.6941

>NTDB_id=865414 Q7580_RS12820 WP_342252012.1 2647731..2648972(-) (cinA) [Enterococcus faecium strain 2016C07-254]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNGVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=865414 Q7580_RS12820 WP_342252012.1 2647731..2648972(-) (cinA) [Enterococcus faecium strain 2016C07-254]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGGTGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.714

100

0.516
  cinA Streptococcus pneumoniae R6

50.714

100

0.516
  cinA Streptococcus pneumoniae Rx1

50.714

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.714

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.33

99.758

0.472
  cinA Streptococcus suis isolate S10

41.787

100

0.419