Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   Q7618_RS10060 Genome accession   NZ_CP131715
Coordinates   1933957..1934898 (-) Length   313 a.a.
NCBI ID   WP_000249536.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2006C08-243     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1928957..1939898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7618_RS10020 (Q7618_09995) comYH 1929449..1930402 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  Q7618_RS10025 (Q7618_10000) - 1930463..1931055 (-) 593 Protein_1949 methyltransferase domain-containing protein -
  Q7618_RS10030 (Q7618_10005) comGG/cglG 1931158..1931604 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  Q7618_RS10035 (Q7618_10010) comGF/cglF 1931582..1932043 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  Q7618_RS10040 (Q7618_10015) comGE/cglE 1932006..1932308 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  Q7618_RS10045 (Q7618_10020) comGD/cglD 1932271..1932705 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  Q7618_RS10050 (Q7618_10025) comGC/cglC 1932668..1932991 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  Q7618_RS10055 (Q7618_10030) comGB/cglB 1932993..1934009 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  Q7618_RS10060 (Q7618_10035) comGA/cglA/cilD 1933957..1934898 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  Q7618_RS10065 (Q7618_10040) - 1934974..1935339 (-) 366 WP_000286415.1 DUF1033 family protein -
  Q7618_RS10070 (Q7618_10045) - 1935490..1936548 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  Q7618_RS10075 (Q7618_10050) nagA 1936711..1937862 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  Q7618_RS10080 (Q7618_10055) - 1938015..1939832 (-) 1818 WP_001220842.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35493.37 Da        Isoelectric Point: 5.8161

>NTDB_id=864541 Q7618_RS10060 WP_000249536.1 1933957..1934898(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 2006C08-243]
MVQEIAQEIIRSAREKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYGNLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=864541 Q7618_RS10060 WP_000249536.1 1933957..1934898(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 2006C08-243]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGGAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAACAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGGAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

95.847

100

0.958
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.544

86.901

0.361