Detailed information NTG0085781

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: STYK_RS10225
• Genome accession: NZ_AP024523
• Coordinates: 2052910..2054091 (+)
• Length: 393 a.a.
• NCBI ID: WP_060627321.1
• Uniprot ID: -
• Organism: Streptococcus toyakuensis strain TP1632
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2047910..2059091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STYK_RS10185 (STYK_19580)	-	2048970..2049512 (+)	543	WP_001158273.1	TetR/AcrR family transcriptional regulator	-
STYK_RS10200 (STYK_19590)	comE	2049755..2050508 (-)	754	Protein_1963	competence system response regulator transcription factor ComE	-
STYK_RS10205 (STYK_19600)	comD/comD1	2050505..2051830 (-)	1326	WP_084923904.1	competence system sensor histidine kinase ComD	Regulator
STYK_RS10210 (STYK_19610)	comC/comC2	2051843..2051965 (-)	123	WP_060627323.1	competence-stimulating peptide ComC	Regulator
STYK_RS10220 (STYK_19620)	rlmH	2052247..2052726 (-)	480	WP_060627322.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
STYK_RS10225 (STYK_19630)	htrA	2052910..2054091 (+)	1182	WP_060627321.1	S1C family serine protease	Regulator
STYK_RS10230 (STYK_19640)	spo0J	2054149..2054907 (+)	759	WP_020902614.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 41679.52 Da
• Isoelectric Point: 6.1486

>NTDB_id=85781 STYK_RS10225 WP_060627321.1 2052910..2054091(+) (htrA) [Streptococcus toyakuensis strain TP1632]
MKHLKTFYKKGFQLLVVIVISFISGALGSFSINQLTQKSTVSTSNNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSA
NRQNSVFGNDDTDTDSQQISSEGSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINIIEQLEKNGKVTRPALGIQMVNLSNINTSDIRRLNIPSNVTSGVV
VRSVQSNMPANGHLEKYDVITKIDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLDKSSGDLES

Nucleotide

• Length: 1182 bp

>NTDB_id=85781 STYK_RS10225 WP_060627321.1 2052910..2054091(+) (htrA) [Streptococcus toyakuensis strain TP1632]
ATGAAACATTTAAAAACATTTTACAAAAAAGGGTTTCAATTATTAGTCGTTATCGTCATTAGCTTTATTAGTGGAGCCTT
GGGTAGCTTTTCAATAAACCAACTAACTCAAAAAAGTACTGTAAGTACCTCTAACAACAATAGTACTATTACACAGACTG
CCTATAAGAATGAAAATTCAACAACACAGGCTGTTAACAAAGTAAAAGATGCTGTTGTTTCAGTTATTACTTATTCAGCA
AACAGACAAAATAGCGTATTTGGTAATGATGATACTGACACAGATTCTCAGCAGATCTCTAGTGAAGGATCTGGGGTTAT
TTATAAAAAGAATGATAAAGAAGCTTATATTGTCACCAATAATCACGTTATAAATGGCGCCAGCAAAGTAGATATTCGTT
TGTCAGATGGAACTAAAGTACCTGGAGAAATCGTCGGAGCTGATACTTTCTCTGATATTGCTGTCGTCAAAATCTCTTCA
GAAAAAGTGACAACAGTAGCTGAATTTGGTGATTCTAGTAAGCTAACCGTAGGAGAAACTGCTATTGCCATTGGTAGCCC
GTTAGGTTCTGAATATGCTAATACTGTCACTCAAGGTATCGTATCTAGTCTTAATCGAAATGTGTCCTTAAAATCTGAAG
ATGGACAAGCCATTTCTACAAAAGCCATCCAAACTGATACTGCTATTAACCCAGGTAACTCTGGTGGTCCACTAATCAAT
ATTCAAGGACAGGTTATCGGAATTACCTCAAGTAAAATTGCCACAAATGGAGGAACATCTGTAGAAGGTCTTGGTTTTGC
AATCCCTGCAAATGATGCTATCAATATTATTGAACAGTTAGAAAAGAACGGAAAAGTAACGCGTCCAGCTTTGGGAATTC
AAATGGTCAATCTCTCAAATATTAATACAAGTGATATTAGAAGACTGAATATTCCAAGCAATGTAACATCTGGTGTAGTT
GTTCGTTCTGTGCAGAGCAATATGCCTGCCAATGGTCACCTTGAAAAATACGATGTTATTACAAAAATAGATGATAAGGA
GATTGCTTCATCAACAGATTTACAAAGTGCTCTTTACAATCATTCTATCGGAGACACCATTAAGATAACTTACTATCGTA
ACGGTAAAGAAGAAACTACATCTATTAAACTTGACAAGAGTTCAGGTGATTTAGAATCTTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (289-384)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	99.237	100	0.992
htrA	Streptococcus pneumoniae Rx1	96.947	100	0.969
htrA	Streptococcus pneumoniae D39	96.947	100	0.969
htrA	Streptococcus pneumoniae R6	96.947	100	0.969
htrA	Streptococcus pneumoniae TIGR4	96.947	100	0.969
htrA	Streptococcus gordonii str. Challis substr. CH1	67.003	100	0.677
htrA	Streptococcus mutans UA159	54.822	100	0.55