Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   STYK_RS10205 Genome accession   NZ_AP024523
Coordinates   2050505..2051830 (-) Length   441 a.a.
NCBI ID   WP_084923904.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2045505..2056830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS10180 (STYK_19570) - 2046200..2048842 (-) 2643 WP_084923902.1 YhgE/Pip domain-containing protein -
  STYK_RS10185 (STYK_19580) - 2048970..2049512 (+) 543 WP_001158273.1 TetR/AcrR family transcriptional regulator -
  STYK_RS10200 (STYK_19590) comE 2049755..2050508 (-) 754 Protein_1963 competence system response regulator transcription factor ComE -
  STYK_RS10205 (STYK_19600) comD/comD1 2050505..2051830 (-) 1326 WP_084923904.1 competence system sensor histidine kinase ComD Regulator
  STYK_RS10210 (STYK_19610) comC/comC2 2051843..2051965 (-) 123 WP_060627323.1 competence-stimulating peptide ComC Regulator
  STYK_RS10220 (STYK_19620) rlmH 2052247..2052726 (-) 480 WP_060627322.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  STYK_RS10225 (STYK_19630) htrA 2052910..2054091 (+) 1182 WP_060627321.1 S1C family serine protease Regulator
  STYK_RS10230 (STYK_19640) spo0J 2054149..2054907 (+) 759 WP_020902614.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51199.81 Da        Isoelectric Point: 7.0707

>NTDB_id=85779 STYK_RS10205 WP_084923904.1 2050505..2051830(-) (comD/comD1) [Streptococcus toyakuensis strain TP1632]
MNFFLVVDFILYFFIISHSYHLICKGQINRKELFFFGAYTLLVEVVLGLPFYLLNLDGLGIARFLFPLGLYSYFRWIKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYYGLFFFVVTVLTYVVIVTIIHYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSNMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMIPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=85779 STYK_RS10205 WP_084923904.1 2050505..2051830(-) (comD/comD1) [Streptococcus toyakuensis strain TP1632]
ATGAATTTTTTCTTAGTAGTAGATTTTATATTATATTTTTTTATTATTAGTCACAGTTACCATTTAATTTGTAAAGGTCA
AATAAATAGAAAAGAATTATTCTTTTTTGGTGCTTATACATTACTAGTAGAAGTAGTACTTGGCCTTCCCTTCTATCTTC
TAAATTTAGATGGGTTAGGGATTGCAAGATTTTTATTTCCTTTGGGCTTATATTCCTATTTTCGATGGATTAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACGTT
CTCCTCTATAACAGGAGACAATTTTGTTTTACAATATTATGGCCTATTCTTTTTCGTTGTAACGGTATTGACTTATGTCG
TTATCGTAACAATCATTCATTATTTCCATTTGGAACTAGCCTATTTTGACAAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTACTGCTCCATATTGTATCTTTCGTTTCAAATATGGTAAGTACGATTAAACATTTGAATAGCTT
TGGAAGTATTTTATCATCTATTGTCTTTATCTCTTTACTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTATACAGATGAAATTGTCGGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGGATGCTTGTCAGTATGCAAATGGCAATTGACAGTGGTGATTTACA
GGAAATTGACAGAGTTTACAATGAAGTTTTGGTCAAAGCAAATCACAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TAAACAATATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCCATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTCCCAATTGAATTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
CAATGCTGTCGAAGGATCGGCTGATAGTTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTGA
TTGTGATTCAGAATTCATGTAAAATGACGATGATTCCTTCAGGAGATCTATTTGCATTAGGATTCTCCACTAAAGGAAGA
AATCGCGGGGTAGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATTATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

92.063

100

0.921
  comD/comD1 Streptococcus pneumoniae D39

92.063

100

0.921
  comD/comD1 Streptococcus pneumoniae R6

92.063

100

0.921
  comD/comD2 Streptococcus pneumoniae TIGR4

93.056

97.959

0.912
  comD Streptococcus mitis SK321

91.156

100

0.912
  comD Streptococcus mitis NCTC 12261

88.209

100

0.882
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.468

85.261

0.422
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.261

0.42

Multiple sequence alignment