Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   STYK_RS10210 Genome accession   NZ_AP024523
Coordinates   2051843..2051965 (-) Length   40 a.a.
NCBI ID   WP_060627323.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 2046843..2056965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS10185 (STYK_19580) - 2048970..2049512 (+) 543 WP_001158273.1 TetR/AcrR family transcriptional regulator -
  STYK_RS10200 (STYK_19590) comE 2049755..2050508 (-) 754 Protein_1963 competence system response regulator transcription factor ComE -
  STYK_RS10205 (STYK_19600) comD/comD1 2050505..2051830 (-) 1326 WP_084923904.1 competence system sensor histidine kinase ComD Regulator
  STYK_RS10210 (STYK_19610) comC/comC2 2051843..2051965 (-) 123 WP_060627323.1 competence-stimulating peptide ComC Regulator
  STYK_RS10220 (STYK_19620) rlmH 2052247..2052726 (-) 480 WP_060627322.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  STYK_RS10225 (STYK_19630) htrA 2052910..2054091 (+) 1182 WP_060627321.1 S1C family serine protease Regulator
  STYK_RS10230 (STYK_19640) spo0J 2054149..2054907 (+) 759 WP_020902614.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4814.65 Da        Isoelectric Point: 11.0668

>NTDB_id=85780 STYK_RS10210 WP_060627323.1 2051843..2051965(-) (comC/comC2) [Streptococcus toyakuensis strain TP1632]
MKNTVKLEQFVALKEKDLQKIQGGEMRKSNNNFFNFLRRI

Nucleotide


Download         Length: 123 bp        

>NTDB_id=85780 STYK_RS10210 WP_060627323.1 2051843..2051965(-) (comC/comC2) [Streptococcus toyakuensis strain TP1632]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAAAAGATTCAAGGTGGGGAGATGAG
GAAATCAAATAATAATTTCTTTAATTTCTTAAGAAGAATATAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

77.5

100

0.775

  comC/comC2 Streptococcus pneumoniae TIGR4

77.5

100

0.775

  comC Streptococcus mitis SK321

72.5

100

0.725

  comC Streptococcus mitis NCTC 12261

69.231

97.5

0.675

  comC/comC1 Streptococcus pneumoniae G54

93.103

72.5

0.675

  comC/comC1 Streptococcus pneumoniae D39

93.103

72.5

0.675

  comC/comC1 Streptococcus pneumoniae Rx1

93.103

72.5

0.675

  comC/comC1 Streptococcus pneumoniae R6

93.103

72.5

0.675


Multiple sequence alignment