Detailed information NTG0851399

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: LLD17_RS10335
• Genome accession: NZ_CP129182
• Coordinates: 1880012..1880593 (-)
• Length: 193 a.a.
• NCBI ID: WP_231097919.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain D.1.7
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1875012..1885593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLD17_RS10305 (LLD17_10340)	-	1875356..1875571 (-)	216	WP_014572212.1	F0F1 ATP synthase subunit C	-
LLD17_RS10310 (LLD17_10345)	-	1875754..1876530 (-)	777	WP_014572211.1	alpha/beta hydrolase family protein	-
LLD17_RS10315 (LLD17_10350)	-	1876814..1877119 (-)	306	Protein_1872	ComEC/Rec2 family competence protein	-
LLD17_RS10320 (LLD17_10355)	-	1877140..1878030 (-)	891	WP_081196833.1	IS982-like element IS982B family transposase	-
LLD17_RS10325 (LLD17_10360)	comEC	1878107..1878616 (-)	510	WP_021165649.1	MBL fold metallo-hydrolase	Machinery gene
LLD17_RS10330 (LLD17_10365)	comEC	1878613..1879884 (-)	1272	WP_324187043.1	ComEC/Rec2 family competence protein	Machinery gene
LLD17_RS10335 (LLD17_10370)	comEA	1880012..1880593 (-)	582	WP_231097919.1	helix-hairpin-helix domain-containing protein	Machinery gene
LLD17_RS10340 (LLD17_10375)	-	1880724..1882085 (-)	1362	WP_081196831.1	ABC transporter permease	-
LLD17_RS10345 (LLD17_10380)	-	1882082..1883014 (-)	933	WP_014572202.1	ABC transporter ATP-binding protein	-
LLD17_RS10350 (LLD17_10385)	-	1883120..1883518 (-)	399	WP_011676775.1	hypothetical protein	-
LLD17_RS10355 (LLD17_10390)	-	1883610..1884194 (-)	585	WP_081196832.1	GNAT family N-acetyltransferase	-
LLD17_RS10360 (LLD17_10395)	-	1884367..1885545 (-)	1179	WP_011676777.1	SLC13 family permease	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21052.51 Da
• Isoelectric Point: 4.8079

>NTDB_id=851399 LLD17_RS10335 WP_231097919.1 1880012..1880593(-) (comEA) [Lactococcus cremoris strain D.1.7]
MEFLYIFTNSPKQAENLSVENLSSSSTKSSVSKFNSSSEKNKNEIMVDLKGAVAKPNVYQISSDERLVDLIRQAGGFTDQ
ADQKSINLSAKLKDEEVIYVPKLGESSSSESTDSPISSSVSNQVSTTSGPKININKADLTELQKLTGIGQKKAQDIIDFR
MKNGDFKSIEDLGKVSGFGDKTLEKLKDEISID

Nucleotide

• Length: 582 bp

>NTDB_id=851399 LLD17_RS10335 WP_231097919.1 1880012..1880593(-) (comEA) [Lactococcus cremoris strain D.1.7]
GTGGAATTTTTATATATTTTCACCAATTCACCAAAGCAAGCTGAAAATCTGTCAGTAGAAAATTTGAGCTCTAGTTCTAC
CAAAAGCTCTGTCAGTAAATTTAATAGCAGCAGTGAAAAAAATAAAAACGAAATTATGGTTGATTTGAAAGGAGCGGTTG
CAAAACCTAATGTATACCAAATTTCGTCAGATGAGCGCCTTGTTGATTTAATTAGGCAAGCGGGAGGATTTACTGACCAA
GCAGACCAAAAATCAATCAATCTGTCAGCGAAACTTAAAGATGAAGAAGTGATTTATGTACCAAAACTTGGGGAAAGTTC
AAGTTCAGAAAGTACTGACAGTCCTATTAGCAGCTCTGTCAGTAATCAAGTTTCAACGACAAGTGGTCCAAAAATAAATA
TCAATAAAGCAGACCTGACAGAATTACAAAAACTGACTGGAATTGGTCAAAAAAAAGCGCAAGATATTATTGATTTTCGC
ATGAAAAATGGTGACTTTAAATCAATAGAGGATTTGGGTAAAGTATCTGGCTTTGGGGATAAAACATTAGAAAAATTGAA
AGATGAGATTTCTATTGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (46-101)

• Helix-hairpin-helix motif (HHH_3) (129-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	94.792	99.482	0.943
comEA/celA/cilE	Streptococcus mitis SK321	45.213	97.409	0.44
comEA	Latilactobacillus sakei subsp. sakei 23K	42.781	96.891	0.415
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	48.993	77.202	0.378
comEA/celA/cilE	Streptococcus pneumoniae R6	48.322	77.202	0.373
comEA/celA/cilE	Streptococcus pneumoniae Rx1	48.322	77.202	0.373
comEA/celA/cilE	Streptococcus pneumoniae D39	48.322	77.202	0.373
comEA/celA/cilE	Streptococcus mitis NCTC 12261	47.651	77.202	0.368
comEA	Staphylococcus aureus MW2	40	90.674	0.363
comEA	Streptococcus thermophilus LMD-9	43.478	83.42	0.363