Detailed information NTG0851366

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: LLUC029_RS11945
• Genome accession: NZ_CP129163
• Coordinates: 2275748..2276773 (-)
• Length: 341 a.a.
• NCBI ID: WP_050595614.1
• Uniprot ID: A0A1V0PEJ1
• Organism: Lactococcus cremoris strain UC029
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2270748..2281773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC029_RS11900 (LLUC029_11925)	-	2270889..2271698 (-)	810	WP_011677177.1	metal ABC transporter permease	-
LLUC029_RS11905 (LLUC029_11930)	-	2271691..2272428 (-)	738	WP_011677178.1	metal ABC transporter ATP-binding protein	-
LLUC029_RS11910 (LLUC029_11935)	-	2272607..2273449 (-)	843	WP_011677179.1	metal ABC transporter solute-binding protein, Zn/Mn family	-
LLUC029_RS11915 (LLUC029_11940)	-	2273446..2273883 (-)	438	WP_011677180.1	zinc-dependent MarR family transcriptional regulator	-
LLUC029_RS11920 (LLUC029_11945)	comGG	2273963..2274190 (-)	228	WP_228764408.1	competence protein ComGG	Machinery gene
LLUC029_RS11925 (LLUC029_11950)	comGF	2274286..2274732 (-)	447	WP_011836043.1	competence type IV pilus minor pilin ComGF	Machinery gene
LLUC029_RS11930 (LLUC029_11955)	comGE	2274695..2274931 (-)	237	WP_014573335.1	competence type IV pilus minor pilin ComGE	Machinery gene
LLUC029_RS11935 (LLUC029_11960)	comGD	2274963..2275151 (-)	189	WP_014573336.1	hypothetical protein	Machinery gene
LLUC029_RS11940 (LLUC029_11965)	comGC	2275353..2275703 (-)	351	WP_050574187.1	competence type IV pilus major pilin ComGC	Machinery gene
LLUC029_RS11945 (LLUC029_11970)	comGB	2275748..2276773 (-)	1026	WP_050595614.1	competence type IV pilus assembly protein ComGB	Machinery gene
LLUC029_RS11950 (LLUC029_11975)	comGA	2276673..2277653 (-)	981	WP_032951299.1	competence type IV pilus ATPase ComGA	Machinery gene
LLUC029_RS11955 (LLUC029_11980)	-	2277768..2281598 (-)	3831	Protein_2329	PolC-type DNA polymerase III	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 38420.20 Da
• Isoelectric Point: 9.9840

>NTDB_id=851366 LLUC029_RS11945 WP_050595614.1 2275748..2276773(-) (comGB) [Lactococcus cremoris strain UC029]
MQTDILRLLRPKGKKLALIKQAKLIQLMGNLLNNGFHLGEVINFLALSKLVEKEFVFKMHQGLSSGNSLSEILDSLSCSK
NVVTQLALVEVHGNLVGTMQLVELHLKKQLKVKKKLIEVATYPVVLLVFLIGIMWGLKNYLLPQIDKGNNFATLLINHLP
LVFFSVGALIVLLTSLSIIIFKHLSALTNFTFLVKVPLVSSFIRLYLTAYFSREWGNLIAQGVELRQIIELMKKQKIRIF
AEVGIKLDLGLKAGQNFEQAVNHFSIFLPELSLMIEYGAIKDKLGLELSVYADECWEQFFSKIDRLMQLIQPLIFIFVAL
MIVLLYAAMSLPIYSNMGSGI

Nucleotide

• Length: 1026 bp

>NTDB_id=851366 LLUC029_RS11945 WP_050595614.1 2275748..2276773(-) (comGB) [Lactococcus cremoris strain UC029]
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAATGGTTTCCATTTGGGAGAAGTTATCAATTTTTTAGCTTTATCAAAATTAGTAGAAAAAG
AGTTTGTATTCAAAATGCACCAAGGTCTCAGTTCTGGAAATTCATTATCTGAAATTTTAGATAGTCTCTCTTGTTCTAAA
AATGTTGTGACACAACTTGCTTTGGTAGAAGTGCATGGGAATTTAGTAGGAACCATGCAATTGGTAGAACTGCATTTAAA
AAAGCAGCTTAAGGTCAAAAAGAAATTAATTGAAGTGGCAACTTATCCAGTTGTATTGTTGGTATTTCTCATTGGAATTA
TGTGGGGCTTGAAAAATTATTTATTACCTCAAATTGATAAGGGAAATAATTTTGCTACTTTATTAATTAATCATTTACCG
CTAGTATTTTTTTCTGTTGGTGCTTTAATCGTTTTACTGACAAGTTTATCAATAATAATATTCAAACATCTTTCAGCACT
CACTAATTTTACTTTTTTGGTTAAAGTTCCATTAGTAAGTTCTTTTATCCGCTTGTATTTGACCGCTTATTTCTCCAGAG
AATGGGGAAATTTAATTGCTCAAGGAGTTGAATTGCGACAAATAATAGAATTGATGAAAAAGCAGAAAATTCGCATTTTT
GCGGAAGTTGGAATTAAACTTGATTTGGGTTTGAAGGCTGGTCAGAATTTTGAGCAAGCTGTCAATCATTTTTCGATTTT
TTTACCAGAACTTTCTTTGATGATTGAGTACGGCGCGATTAAAGATAAATTAGGGTTGGAGCTTTCTGTTTATGCTGATG
AATGTTGGGAACAATTCTTTTCTAAGATAGACCGTCTAATGCAATTAATACAACCCCTTATTTTTATTTTTGTTGCTTTG
ATGATTGTCTTATTGTATGCAGCGATGTCGTTACCCATTTATTCTAATATGGGTTCTGGAATTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (211-332)

• Type II secretion system (T2SS), protein F (T2SSF) (25-143)

3D structure

• AlphaFold DB: A0A1V0PEJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	97.361	100	0.974
comYB	Streptococcus gordonii str. Challis substr. CH1	51.039	98.827	0.504
comGB/cglB	Streptococcus pneumoniae D39	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae R6	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae Rx1	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae TIGR4	50.299	97.947	0.493
comGB/cglB	Streptococcus mitis SK321	50	97.947	0.49
comGB/cglB	Streptococcus mitis NCTC 12261	49.102	97.947	0.481
comYB	Streptococcus mutans UA140	50.955	92.082	0.469
comYB	Streptococcus mutans UA159	50.318	92.082	0.463