Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   LLUC320_RS11090 Genome accession   NZ_CP129095
Coordinates   2157448..2158473 (-) Length   341 a.a.
NCBI ID   WP_050574185.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UC320     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2151123..2159353 2157448..2158473 within 0


Gene organization within MGE regions


Location: 2151123..2159353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC320_RS11045 (LLUC320_11105) - 2152589..2153398 (-) 810 WP_011677177.1 metal ABC transporter permease -
  LLUC320_RS11050 (LLUC320_11110) - 2153391..2154128 (-) 738 WP_011677178.1 metal ABC transporter ATP-binding protein -
  LLUC320_RS11055 (LLUC320_11115) - 2154307..2155149 (-) 843 WP_011677179.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LLUC320_RS11060 (LLUC320_11120) - 2155146..2155583 (-) 438 WP_011677180.1 zinc-dependent MarR family transcriptional regulator -
  LLUC320_RS11065 (LLUC320_11125) comGG 2155663..2155890 (-) 228 WP_228764408.1 competence protein ComGG Machinery gene
  LLUC320_RS11070 (LLUC320_11130) comGF 2155986..2156411 (-) 426 WP_014735174.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLUC320_RS11075 (LLUC320_11135) comGE 2156395..2156631 (-) 237 WP_014573335.1 competence type IV pilus minor pilin ComGE Machinery gene
  LLUC320_RS11080 (LLUC320_11140) comGD 2156663..2156851 (-) 189 WP_014573336.1 hypothetical protein Machinery gene
  LLUC320_RS11085 (LLUC320_11145) comGC 2157053..2157430 (-) 378 Protein_2156 competence type IV pilus major pilin ComGC -
  LLUC320_RS11090 (LLUC320_11150) comGB 2157448..2158473 (-) 1026 WP_050574185.1 competence type IV pilus assembly protein ComGB Machinery gene
  LLUC320_RS11095 (LLUC320_11155) comGA 2158373..2159353 (-) 981 WP_162494683.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 341 a.a.        Molecular weight: 38393.18 Da        Isoelectric Point: 9.9840

>NTDB_id=850850 LLUC320_RS11090 WP_050574185.1 2157448..2158473(-) (comGB) [Lactococcus cremoris strain UC320]
MQTDILRLLRPKGKKLALIKQAKLIQLMGNLLNNGFHLGEVINFLALSKLVEKEFVFKMHQGLSSGNSLSEILDSLSCSK
NVVTQLALVEVHGNLVGTMQLVELHLKKQLKVKKKLIEVATYPVVLLVFLIGIMWGLKNYLLPQIDKGNNFATLLINHLP
LVFFSVGALIVLLTSLSIIIFKHLSALTNFTFLVKVPLVSSFIRLYLTAYFSREWGNLIAQGVELRQIIELMKKQKIRIF
AEVGIKLDLGLKAGQNFEQAVSHFSIFLPELSLMIEYGAIKDKLGLELSVYADECWEQFFSKIDRLMQLIQPLIFIFVAL
MIVLLYAAMSLPIYSNMGSGI

Nucleotide


Download         Length: 1026 bp        

>NTDB_id=850850 LLUC320_RS11090 WP_050574185.1 2157448..2158473(-) (comGB) [Lactococcus cremoris strain UC320]
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAATGGTTTCCATTTGGGAGAAGTTATCAATTTTTTAGCTTTATCAAAATTAGTAGAAAAAG
AGTTTGTATTCAAAATGCACCAAGGTCTCAGTTCTGGAAATTCATTATCTGAAATTTTAGATAGTCTCTCTTGTTCTAAA
AATGTTGTGACACAACTTGCTTTGGTAGAAGTGCATGGGAATTTAGTAGGAACCATGCAATTGGTAGAACTGCATTTAAA
AAAGCAGCTTAAGGTCAAAAAGAAATTAATTGAAGTGGCAACTTATCCAGTTGTATTGTTGGTATTTCTCATTGGAATTA
TGTGGGGCTTGAAAAATTATTTATTACCTCAAATTGATAAGGGAAATAATTTTGCTACTTTATTAATTAATCATTTACCG
CTAGTATTTTTTTCTGTTGGTGCTTTAATCGTTTTACTGACAAGTTTATCAATAATAATATTCAAACATCTTTCAGCACT
CACTAATTTTACTTTTTTGGTTAAAGTTCCATTAGTAAGTTCTTTTATCCGCTTGTATTTGACCGCTTATTTCTCCAGAG
AATGGGGAAATTTAATTGCTCAAGGAGTTGAATTGCGACAAATAATAGAATTGATGAAAAAGCAGAAAATTCGCATTTTT
GCGGAAGTTGGAATTAAACTTGATTTGGGTTTGAAGGCTGGTCAGAATTTTGAGCAAGCTGTCAGTCATTTTTCGATTTT
TTTACCAGAACTTTCTTTGATGATTGAGTACGGCGCGATTAAAGATAAATTAGGGTTGGAGCTTTCTGTTTATGCTGATG
AATGTTGGGAACAATTCTTTTCTAAGATAGACCGTCTAATGCAATTAATACAACCCCTTATTTTTATTTTTGTTGCTTTG
ATGATTGTCTTATTGTATGCAGCGATGTCGTTACCCATTTATTCTAATATGGGTTCTGGAATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(211-332)

Type II secretion system (T2SS), protein F (T2SSF)

(25-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

97.654

100

0.977
  comYB Streptococcus gordonii str. Challis substr. CH1

51.039

98.827

0.504
  comGB/cglB Streptococcus pneumoniae D39

50.299

97.947

0.493
  comGB/cglB Streptococcus pneumoniae R6

50.299

97.947

0.493
  comGB/cglB Streptococcus pneumoniae Rx1

50.299

97.947

0.493
  comGB/cglB Streptococcus pneumoniae TIGR4

50.299

97.947

0.493
  comGB/cglB Streptococcus mitis SK321

50

97.947

0.49
  comGB/cglB Streptococcus mitis NCTC 12261

49.102

97.947

0.481
  comYB Streptococcus mutans UA140

50.955

92.082

0.469
  comYB Streptococcus mutans UA159

50.318

92.082

0.463