Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QWG62_RS08220 Genome accession   NZ_CP128995
Coordinates   1488308..1489549 (+) Length   413 a.a.
NCBI ID   WP_002293079.1    Uniprot ID   A0AB73A9G3
Organism   Enterococcus faecium strain AK_C_05     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1483308..1494549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWG62_RS08200 (QWG62_08200) - 1483389..1484657 (+) 1269 WP_047929451.1 pitrilysin family protein -
  QWG62_RS08205 (QWG62_08205) - 1484650..1485936 (+) 1287 WP_002293084.1 pitrilysin family protein -
  QWG62_RS08210 (QWG62_08210) - 1486428..1487351 (+) 924 WP_002310444.1 RodZ domain-containing protein -
  QWG62_RS08215 (QWG62_08215) pgsA 1487560..1488137 (+) 578 Protein_1445 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QWG62_RS08220 (QWG62_08220) cinA 1488308..1489549 (+) 1242 WP_002293079.1 competence/damage-inducible protein A Machinery gene
  QWG62_RS08225 (QWG62_08225) recA 1489658..1490707 (+) 1050 WP_002293077.1 recombinase RecA Machinery gene
  QWG62_RS08230 (QWG62_08230) rny 1491126..1492682 (+) 1557 WP_002287336.1 ribonuclease Y -
  QWG62_RS08235 (QWG62_08235) proC 1492761..1493567 (-) 807 WP_002293075.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45406.91 Da        Isoelectric Point: 4.8009

>NTDB_id=850332 QWG62_RS08220 WP_002293079.1 1488308..1489549(+) (cinA) [Enterococcus faecium strain AK_C_05]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKANKQTVTAAESLTAGAFQAALGDIAGVSDVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDMLEGHPAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=850332 QWG62_RS08220 WP_002293079.1 1488308..1489549(+) (cinA) [Enterococcus faecium strain AK_C_05]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAGACAGTCGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGGCCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCTCAAATCATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCATATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTGATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAACTAAAAGATCTGATTGAAACACAGATCAATCCAACGATCGCTCCTTATGCCA
AACCAAATGAAGTGACATTGCGTCTAACAGTGAAAACAAAGGATGTTCAGGCAGGAAATCAAGCTCTTTTAGCATTGGAA
GAAAAGATTCAAGAACGAGTAGGAGAATATTTTTATGGATATGGCGATGATAATTCGTTAGCAAAAGTCGTAGTGGAACT
GCTGAAAGCAAACAAGCAGACTGTAACAGCGGCGGAAAGCTTGACAGCCGGTGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGATGTATTTCCAGGCGGCTTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACATGTTAGAAGGTCACCCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGATGGCGTGGTTTCAGAAAAATATCATTTTGCCAGAGACCGTGCGGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.667

100

0.525
  cinA Streptococcus pneumoniae TIGR4

51.429

100

0.523
  cinA Streptococcus pneumoniae D39

51.19

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.19

100

0.521
  cinA Streptococcus pneumoniae R6

51.19

100

0.521
  cinA Streptococcus mitis NCTC 12261

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.546

100

0.416