Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   V2198_RS09480 Genome accession   NZ_CP143900
Coordinates   2025586..2026803 (-) Length   405 a.a.
NCBI ID   WP_033995372.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain PA19_NI3_44.22_ST207     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2020586..2031803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2198_RS09435 (V2198_09435) - 2020770..2021219 (-) 450 WP_003094670.1 MOSC domain-containing protein -
  V2198_RS09440 (V2198_09440) - 2021216..2021845 (-) 630 WP_003094668.1 DUF1780 domain-containing protein -
  V2198_RS09445 (V2198_09445) - 2021978..2022403 (+) 426 WP_003094666.1 GNAT family N-acetyltransferase -
  V2198_RS09450 (V2198_09450) - 2022400..2022870 (+) 471 WP_003094664.1 hypothetical protein -
  V2198_RS09455 (V2198_09455) - 2022867..2023556 (+) 690 WP_003094662.1 energy-coupling factor ABC transporter permease -
  V2198_RS09460 (V2198_09460) - 2023662..2023871 (+) 210 WP_003094660.1 hypothetical protein -
  V2198_RS09465 (V2198_09465) yacG 2023908..2024108 (-) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  V2198_RS09470 (V2198_09470) coaE 2024105..2024716 (-) 612 WP_003094654.1 dephospho-CoA kinase -
  V2198_RS09475 (V2198_09475) pilD 2024713..2025585 (-) 873 WP_023092875.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  V2198_RS09480 (V2198_09480) pilC 2025586..2026803 (-) 1218 WP_033995372.1 type II secretion system F family protein Machinery gene
  V2198_RS09485 (V2198_09485) pilB 2026807..2028507 (-) 1701 WP_023092873.1 type IV-A pilus assembly ATPase PilB Machinery gene
  V2198_RS09490 (V2198_09490) pilA/pilAI 2028738..2029202 (+) 465 WP_023092872.1 pilin Machinery gene
  V2198_RS09495 (V2198_09495) - 2029358..2030671 (+) 1314 WP_231280937.1 O-antigen ligase family protein -
  V2198_RS09505 (V2198_09505) nadC 2030852..2031700 (-) 849 WP_033995373.1 carboxylating nicotinate-nucleotide diphosphorylase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44086.87 Da        Isoelectric Point: 9.7134

>NTDB_id=844976 V2198_RS09480 WP_033995372.1 2025586..2026803(-) (pilC) [Pseudomonas aeruginosa strain PA19_NI3_44.22_ST207]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVASGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTQMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVDKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=844976 V2198_RS09480 WP_033995372.1 2025586..2026803(-) (pilC) [Pseudomonas aeruginosa strain PA19_NI3_44.22_ST207]
ATGGCGGACAAAGCGTTAAAAACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TTTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATGGACATCGCACTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCCGGCGTGCCACTGCTGCAGTCGTTCGACATCATCAGCGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGA
GATCAAGCAGGAAGTCGCCAGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACT
GCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTGGAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCAATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCGGCCTTCACCCAAATGG
TCATCAATATCTCCAACGTGCTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTTCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCGATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGACAAGATCAAGCAGGACGTTTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTCCCCAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
TTGGGCAACGTCGTCTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baylyi ADP1

61.029

100

0.615
  pilC Acinetobacter baumannii D1279779

60.396

99.753

0.602
  pilC Legionella pneumophila strain ERS1305867

54.545

97.778

0.533
  pilG Neisseria gonorrhoeae MS11

46.287

99.753

0.462
  pilG Neisseria meningitidis 44/76-A

45.771

99.259

0.454
  pilC Vibrio cholerae strain A1552

41.728

100

0.417
  pilC Vibrio campbellii strain DS40M4

40.852

98.519

0.402
  pilC Thermus thermophilus HB27

37.905

99.012

0.375