Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   QQS40_RS00235 Genome accession   NZ_CP127167
Coordinates   48022..48465 (+) Length   147 a.a.
NCBI ID   WP_075875764.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain HP01     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 43022..53465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQS40_RS00200 tadA 43238..43729 (-) 492 WP_420485554.1 tRNA adenosine(34) deaminase TadA -
  QQS40_RS00205 - 43766..44617 (-) 852 WP_329505438.1 thymidylate synthase -
  QQS40_RS00210 lgt 44628..45437 (-) 810 WP_329505440.1 prolipoprotein diacylglyceryl transferase -
  QQS40_RS00215 - 45446..46240 (-) 795 WP_329505442.1 sulfite exporter TauE/SafE family protein -
  QQS40_RS00220 rppH 46240..46833 (-) 594 WP_329505444.1 RNA pyrophosphohydrolase -
  QQS40_RS00225 ampD 47318..47881 (-) 564 WP_329505446.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  QQS40_RS00230 - 47874..48032 (-) 159 WP_329505448.1 hypothetical protein -
  QQS40_RS00235 pilA 48022..48465 (+) 444 WP_075875764.1 prepilin peptidase-dependent pilin Machinery gene
  QQS40_RS00240 pilB 48472..49851 (+) 1380 WP_329505451.1 GspE/PulE family protein Machinery gene
  QQS40_RS00245 pilC 49860..51083 (+) 1224 WP_128786982.1 type II secretion system F family protein Machinery gene
  QQS40_RS00250 pilD 51080..51757 (+) 678 WP_329505454.1 A24 family peptidase Machinery gene
  QQS40_RS00255 coaE 51843..52463 (+) 621 WP_329505456.1 dephospho-CoA kinase -
  QQS40_RS00260 yacG 52456..52662 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  QQS40_RS00265 - 52659..52940 (+) 282 WP_329505459.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 147 a.a.        Molecular weight: 15121.39 Da        Isoelectric Point: 8.4674

>NTDB_id=842300 QQS40_RS00235 WP_075875764.1 48022..48465(+) (pilA) [Haemophilus parainfluenzae strain HP01]
MKLTFSKPLHKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAISELLQASAPYKSDVELCVYSTNAPTNCSGGSNGIA
ADITTAKGYVKSITTKSGVITVTGNGALDGISYSLTATGSTSSGVTWTTACPSNADLFPAGFCSPAK

Nucleotide


Download         Length: 444 bp        

>NTDB_id=842300 QQS40_RS00235 WP_075875764.1 48022..48465(+) (pilA) [Haemophilus parainfluenzae strain HP01]
ATGAAACTCACTTTTTCTAAACCTTTGCATAAAGGTTTTACGTTAATTGAATTGATGATCGTGATTGCGATTATTGCTAT
TCTCGCGACGATCGCCATTCCGTCTTATCAAAATTATACCAAAAAAGCAGCCATCTCCGAATTATTGCAAGCTTCGGCAC
CTTATAAATCTGATGTGGAGTTATGCGTCTATAGCACCAATGCCCCGACAAACTGTTCAGGTGGTTCAAATGGCATTGCA
GCAGACATCACTACTGCAAAAGGCTATGTTAAATCCATTACCACGAAATCGGGTGTGATTACGGTAACAGGAAATGGCGC
ATTGGATGGGATCAGTTATTCTTTAACGGCGACAGGCTCAACCTCATCAGGTGTCACCTGGACAACCGCTTGCCCAAGCA
ATGCGGATTTATTCCCAGCAGGTTTCTGCTCTCCAGCCAAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(10-32)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Haemophilus influenzae 86-028NP

75.694

97.959

0.741
  pilA Haemophilus influenzae Rd KW20

73.611

97.959

0.721
  pilA Glaesserella parasuis strain SC1401

56.081

100

0.565
  pilA Vibrio campbellii strain DS40M4

41.096

99.32

0.408
  pilE Neisseria gonorrhoeae MS11

41.985

89.116

0.374
  pilA2 Legionella pneumophila str. Paris

42.188

87.075

0.367