Detailed information NTG0839386

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: LLE01_RS12470
• Genome accession: NZ_CP126675
• Coordinates: 2256928..2257311 (-)
• Length: 127 a.a.
• NCBI ID: WP_010906318.1
• Uniprot ID: A0A3N6KXZ7
• Organism: Lactococcus lactis subsp. lactis strain E.0.1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2251928..2262311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLE01_RS12430 (LLE01_12400)	-	2252464..2253273 (-)	810	WP_010906310.1	metal ABC transporter permease	-
LLE01_RS12435 (LLE01_12405)	-	2253266..2254003 (-)	738	WP_010906311.1	metal ABC transporter ATP-binding protein	-
LLE01_RS12440 (LLE01_12410)	-	2254180..2255022 (-)	843	WP_010906312.1	metal ABC transporter substrate-binding protein	-
LLE01_RS12445 (LLE01_12415)	-	2255019..2255456 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
LLE01_RS12450 (LLE01_12420)	comGG	2255537..2255821 (-)	285	WP_010906314.1	competence type IV pilus minor pilin ComGG	Machinery gene
LLE01_RS12455 (LLE01_12425)	comGF	2255860..2256306 (-)	447	WP_031296844.1	competence type IV pilus minor pilin ComGF	Machinery gene
LLE01_RS12460 (LLE01_12430)	comGE	2256269..2256565 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
LLE01_RS12465 (LLE01_12435)	comGD	2256537..2256935 (-)	399	WP_021214886.1	competence type IV pilus minor pilin ComGD	Machinery gene
LLE01_RS12470 (LLE01_12440)	comGC	2256928..2257311 (-)	384	WP_010906318.1	competence type IV pilus major pilin ComGC	Machinery gene
LLE01_RS12475 (LLE01_12445)	comGB	2257325..2258398 (-)	1074	WP_010906319.1	competence type IV pilus assembly protein ComGB	Machinery gene
LLE01_RS12480 (LLE01_12450)	comGA	2258292..2259230 (-)	939	WP_010906320.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 127 a.a.
• Molecular weight: 14797.39 Da
• Isoelectric Point: 8.4538

>NTDB_id=839386 LLE01_RS12470 WP_010906318.1 2256928..2257311(-) (comGC) [Lactococcus lactis subsp. lactis strain E.0.1]
MERTKKFILKKIQKIFLFVKICEKKCRQKELKAFTLIEMLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQA
QLYELDHDDEKPSLSELLSAGMITQKQISAYDNYYDQNKNEERNFND

Nucleotide

• Length: 384 bp

>NTDB_id=839386 LLE01_RS12470 WP_010906318.1 2256928..2257311(-) (comGC) [Lactococcus lactis subsp. lactis strain E.0.1]
ATGGAAAGAACAAAGAAGTTTATTTTAAAAAAAATACAAAAAATATTTTTATTCGTTAAAATTTGTGAAAAAAAATGCCG
TCAGAAAGAGCTAAAAGCTTTTACTTTGATAGAGATGTTAATTGTACTAGCTATTATTAGTATTTTGATATTACTATTTG
TTCCAAATTTAATTAAAGAAAAATCACAAGTTCAAAAAACTGGAGAAGCGGCAGTTGTCAAAGTAGTAGAAAGTCAAGCT
CAACTTTATGAATTAGATCATGATGATGAGAAGCCGAGTCTGTCAGAATTGCTCAGTGCAGGGATGATTACTCAAAAACA
AATTTCTGCTTACGATAATTACTATGATCAGAATAAAAATGAAGAACGAAATTTTAATGACTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (32-52)

3D structure

• AlphaFold DB: A0A3N6KXZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Lactococcus lactis subsp. cremoris KW2	81.034	91.339	0.74
comGC/cglC	Streptococcus mitis SK321	56.436	79.528	0.449
comYC	Streptococcus mutans UA159	55.446	79.528	0.441
comYC	Streptococcus mutans UA140	55.446	79.528	0.441
comYC	Streptococcus gordonii str. Challis substr. CH1	56.566	77.953	0.441
comGC/cglC	Streptococcus pneumoniae TIGR4	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae Rx1	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae D39	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae R6	54.455	79.528	0.433
comGC/cglC	Streptococcus mitis NCTC 12261	58.427	70.079	0.409
comYC	Streptococcus suis isolate S10	56.818	69.291	0.394