Detailed information NTG0083446

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: Hhaem_RS09235
• Genome accession: NZ_AP024093
• Coordinates: 1878487..1879164 (+)
• Length: 225 a.a.
• NCBI ID: WP_005627381.1
• Uniprot ID: -
• Organism: Haemophilus haemolyticus strain 2019-19
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1873487..1884164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Hhaem_RS09195 (Hhaem_17490)	mutM	1873516..1874331 (-)	816	WP_223893576.1	DNA-formamidopyrimidine glycosylase	-
Hhaem_RS09200 (Hhaem_17500)	rpmG	1874403..1874573 (-)	171	WP_005613503.1	50S ribosomal protein L33	-
Hhaem_RS09205 (Hhaem_17510)	rpmB	1874585..1874821 (-)	237	WP_005599762.1	50S ribosomal protein L28	-
Hhaem_RS09210 (Hhaem_17520)	radC	1875035..1875700 (-)	666	WP_005631435.1	DNA repair protein RadC	-
Hhaem_RS09215 (Hhaem_17530)	coaBC	1875864..1877066 (+)	1203	WP_223893578.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
Hhaem_RS09220 (Hhaem_17540)	dut	1877114..1877569 (+)	456	WP_118855298.1	dUTP diphosphatase	-
Hhaem_RS09225 (Hhaem_17550)	slmA	1877573..1878229 (+)	657	WP_005645921.1	nucleoid occlusion factor SlmA	-
Hhaem_RS09230 (Hhaem_17560)	-	1878251..1878502 (+)	252	WP_005631427.1	YheU family protein	-
Hhaem_RS09235 (Hhaem_17570)	crp	1878487..1879164 (+)	678	WP_005627381.1	cAMP-activated global transcriptional regulator CRP	Regulator
Hhaem_RS09240 (Hhaem_17580)	rlmC	1879530..1880708 (-)	1179	WP_223893580.1	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	-
Hhaem_RS09245 (Hhaem_17590)	nagZ	1880705..1881757 (-)	1053	WP_223893582.1	beta-N-acetylhexosaminidase	-
Hhaem_RS09250 (Hhaem_17600)	-	1881761..1882111 (-)	351	WP_118843544.1	YcfL family protein	-
Hhaem_RS09255 (Hhaem_17610)	hinT	1882111..1882461 (-)	351	WP_223893584.1	purine nucleoside phosphoramidase	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25280.97 Da
• Isoelectric Point: 6.6054

>NTDB_id=83446 Hhaem_RS09235 WP_005627381.1 1878487..1879164(+) (crp) [Haemophilus haemolyticus strain 2019-19]
MSNELTEIDEVVTSSQEEETTQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSAKDDEGKEMILTYL
GAGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIA
QTLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 678 bp

>NTDB_id=83446 Hhaem_RS09235 WP_005627381.1 1878487..1879164(+) (crp) [Haemophilus haemolyticus strain 2019-19]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGAGACAACTCAACGAGATCCAGTTTT
AGATTGGTTTCTTACTCACTGCCATTTACATAAATATCCCGCAAAATCGACTTTAATTCACGCAGGTGAAGATGCAACGA
CACTTTATTATGTCATTAAAGGCTCTGTAATGGTGTCAGCAAAAGATGATGAAGGTAAAGAAATGATTCTCACTTATTTG
GGGGCAGGACAATTCTTTGGTGAAGCTGGATTATTTGATGAAGGCTCAAAACGATCTGCTTGGGTAAAAACAAAAACAAC
ATGTGAAATTGCTGAAATTTCTTATAAAAAATATCGTCAATTAATTCAAGCCAACCCAGAAATCTTAATGTTTTTAACCG
CACAATTGGCAAGACGTTTACAAAATACTTCACGCCAAGTCAGTAATTTAGCATTCTTAGATGTGGCAGGTCGTATTGCC
CAAACGCTAATGAACTTAGCTAAACAGCCTGAAGCAATGACCCATCCTGATGGGATGCAAATCAAAATTACACGTCAAGA
AATAGGGCAAATGGTCGGTTGTTCACGAGAAACTGTAGGACGTATTATTAAGATGTTAGAGGATCAGAACCTTATCCATG
CTCATGGAAAAACCATTGTTGTATATGGTGCAAGATAA

Domains

Predicted by InterproScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (37-125)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (157-221)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	98.222	100	0.982
crp	Vibrio cholerae strain A1552	75.49	90.667	0.684
crp	Acinetobacter baumannii D1279779	48.187	85.778	0.413