Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H7678_RS02025 Genome accession   NZ_AP023393
Coordinates   381671..382357 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain 89     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 376671..387357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7678_RS02000 (SDSE89_03380) ktrB 376778..378154 (-) 1377 WP_065355470.1 potassium uptake transporter channel subunit KtrB -
  H7678_RS02005 (SDSE89_03390) rsmG 378238..378951 (-) 714 WP_046177609.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H7678_RS02010 (SDSE89_03400) - 379104..379661 (+) 558 WP_003058947.1 LemA family protein -
  H7678_RS02015 (SDSE89_03410) htpX 379708..380601 (+) 894 WP_003059035.1 zinc metalloprotease HtpX -
  H7678_RS02020 (SDSE89_03420) - 380868..381401 (+) 534 WP_003058949.1 DUF177 domain-containing protein -
  H7678_RS02025 (SDSE89_03430) covR 381671..382357 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  H7678_RS02030 (SDSE89_03440) - 382363..383862 (+) 1500 WP_065355471.1 ATP-binding protein -
  H7678_RS02035 (SDSE89_03450) nrdR 384068..384562 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  H7678_RS02040 (SDSE89_03460) - 384546..385724 (+) 1179 WP_012766597.1 DnaD domain protein -
  H7678_RS02045 (SDSE89_03470) dnaI 385725..386627 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=82991 H7678_RS02025 WP_003049736.1 381671..382357(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=82991 H7678_RS02025 WP_003049736.1 381671..382357(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment