Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H7679_RS00750 Genome accession   NZ_AP023392
Coordinates   121422..122372 (+) Length   316 a.a.
NCBI ID   WP_024382125.1    Uniprot ID   A0A075SNN5
Organism   Streptococcus suis strain DAT300     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116422..127372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS00740 (DAT300_01130) - 119986..120351 (+) 366 WP_024395451.1 DUF1033 family protein -
  H7679_RS00745 (DAT300_01140) - 120386..121336 (-) 951 WP_024395450.1 S66 peptidase family protein -
  H7679_RS00750 (DAT300_01150) comYA 121422..122372 (+) 951 WP_024382125.1 competence type IV pilus ATPase ComGA Machinery gene
  H7679_RS00755 (DAT300_01160) comYB 122284..123321 (+) 1038 WP_050573097.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7679_RS00760 (DAT300_01170) - 123402..124841 (-) 1440 WP_172077518.1 recombinase family protein -
  H7679_RS00765 (DAT300_01180) - 124976..125545 (-) 570 WP_197970253.1 hypothetical protein -
  H7679_RS00770 (DAT300_01190) - 125559..126317 (-) 759 WP_105131553.1 helix-turn-helix domain-containing protein -
  H7679_RS00775 (DAT300_01200) - 126517..126720 (+) 204 WP_105131554.1 helix-turn-helix domain-containing protein -
  H7679_RS00780 (DAT300_01210) - 126775..127032 (+) 258 WP_105131555.1 hypothetical protein -
  H7679_RS00785 (DAT300_01220) - 127008..127154 (+) 147 WP_184495818.1 BOW99_gp33 family protein -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35384.31 Da        Isoelectric Point: 5.6934

>NTDB_id=82927 H7679_RS00750 WP_024382125.1 121422..122372(+) (comYA) [Streptococcus suis strain DAT300]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDMAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQDGMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=82927 H7679_RS00750 WP_024382125.1 121422..122372(+) (comYA) [Streptococcus suis strain DAT300]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACATGGCTGAGGAGGAAGTAATAGCCA
TCATTAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCGCTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCTGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAGTTTCCAGACAAGCAA
ATTTTGACCATTGAAGATCCTGTAGAAATCAAGCAGGACGGGATGTTGCAGCTCCAGCTCAATGAAGCCATCGGAGCTAC
CTACGATAATCTGATTAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACAGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAACTGGGGGTCAGTCCTGAAGAGCTAAACAATGCCCTTCAAGGCATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTGGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGGC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SNN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA140

68.167

98.418

0.671
  comYA Streptococcus mutans UA159

68.167

98.418

0.671
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

52.997

100

0.532

Multiple sequence alignment