Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QLQ38_RS12600 Genome accession   NZ_CP124890
Coordinates   2642596..2643840 (-) Length   414 a.a.
NCBI ID   WP_010820333.1    Uniprot ID   -
Organism   Enterococcus faecalis strain EfsPF2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2637596..2648840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLQ38_RS12580 (QLQ38_12580) - 2638066..2638452 (-) 387 WP_002359008.1 YlbF family regulator -
  QLQ38_RS12585 (QLQ38_12585) - 2638526..2639323 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  QLQ38_RS12590 (QLQ38_12590) rny 2639483..2641039 (-) 1557 WP_002354863.1 ribonuclease Y -
  QLQ38_RS12595 (QLQ38_12595) recA 2641436..2642482 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  QLQ38_RS12600 (QLQ38_12600) cinA 2642596..2643840 (-) 1245 WP_010820333.1 competence/damage-inducible protein A Machinery gene
  QLQ38_RS12605 (QLQ38_12605) - 2644032..2645237 (+) 1206 WP_048949540.1 hypothetical protein -
  QLQ38_RS12610 (QLQ38_12610) - 2645313..2645942 (-) 630 WP_161797706.1 NAD(P)-dependent oxidoreductase -
  QLQ38_RS12615 (QLQ38_12615) - 2646001..2646426 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  QLQ38_RS12620 (QLQ38_12620) - 2646515..2646898 (-) 384 WP_002358999.1 YccF domain-containing protein -
  QLQ38_RS12625 (QLQ38_12625) - 2647062..2647853 (+) 792 WP_048949542.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45221.34 Da        Isoelectric Point: 4.6698

>NTDB_id=828843 QLQ38_RS12600 WP_010820333.1 2642596..2643840(-) (cinA) [Enterococcus faecalis strain EfsPF2]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVVECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=828843 QLQ38_RS12600 WP_010820333.1 2642596..2643840(-) (cinA) [Enterococcus faecalis strain EfsPF2]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCTATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACTGTTGTAGAATGTTTCCATTTTAACCGTGATCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGACGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437