Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H7677_RS00380 Genome accession   NZ_AP023391
Coordinates   66384..67565 (+) Length   393 a.a.
NCBI ID   WP_184493697.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 61384..72565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS00360 (DAT299_00520) ruvA 63339..63929 (+) 591 WP_184493695.1 Holliday junction branch migration protein RuvA -
  H7677_RS00365 (DAT299_00530) - 64559..65119 (+) 561 WP_023369037.1 DNA-3-methyladenine glycosylase I -
  H7677_RS00370 (DAT299_00540) - 65193..65603 (+) 411 WP_172055386.1 helix-turn-helix transcriptional regulator -
  H7677_RS00375 (DAT299_00550) - 65576..66241 (+) 666 WP_024381977.1 CPBP family intramembrane glutamic endopeptidase -
  H7677_RS00380 (DAT299_00560) cinA 66384..67565 (+) 1182 WP_184493697.1 competence/damage-inducible protein A Machinery gene
  H7677_RS00385 (DAT299_00570) recA 67617..68768 (+) 1152 WP_184493699.1 recombinase RecA Machinery gene
  H7677_RS00390 (DAT299_00580) spx 69004..69402 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  H7677_RS00395 (DAT299_00590) - 69502..69768 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  H7677_RS00400 (DAT299_00600) ruvX 69768..70187 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  H7677_RS00405 (DAT299_00610) - 70199..70519 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  H7677_RS00410 (DAT299_00620) - 70726..71304 (+) 579 WP_044669569.1 nucleotidyltransferase family protein -
  H7677_RS00415 (DAT299_00630) comX/sigX 71378..71644 (+) 267 WP_024383069.1 hypothetical protein Regulator
  H7677_RS00420 (DAT299_00640) rpsJ 71966..72274 (+) 309 WP_014735259.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42996.88 Da        Isoelectric Point: 4.4112

>NTDB_id=82869 H7677_RS00380 WP_184493697.1 66384..67565(+) (cinA) [Streptococcus suis strain DAT299]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAIGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIAEQGTGGLLQAELNLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=82869 H7677_RS00380 WP_184493697.1 66384..67565(+) (cinA) [Streptococcus suis strain DAT299]
ATGAAAGCAGAACTAATCGCTGTGGGTACAGAGATTTTGACAGGACAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAAGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTATTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGCCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAACCTGGCTT
TGGCTGATCAACCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATATCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.183

100

0.962
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

42.44

95.929

0.407

Multiple sequence alignment