Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QJQ46_RS11565 Genome accession   NZ_CP124778
Coordinates   2443250..2444494 (+) Length   414 a.a.
NCBI ID   WP_010706982.1    Uniprot ID   R3KLJ2
Organism   Enterococcus faecalis strain HL1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2438250..2449494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJQ46_RS11540 (QJQ46_11540) - 2439235..2440026 (-) 792 WP_010713701.1 hypothetical protein -
  QJQ46_RS11545 (QJQ46_11545) - 2440190..2440573 (+) 384 WP_002358999.1 YccF domain-containing protein -
  QJQ46_RS11550 (QJQ46_11550) - 2440662..2441087 (+) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  QJQ46_RS11555 (QJQ46_11555) - 2441146..2441775 (+) 630 WP_025188758.1 NAD(P)-dependent oxidoreductase -
  QJQ46_RS11560 (QJQ46_11560) - 2441853..2443058 (-) 1206 WP_016618614.1 hypothetical protein -
  QJQ46_RS11565 (QJQ46_11565) cinA 2443250..2444494 (+) 1245 WP_010706982.1 competence/damage-inducible protein A Machinery gene
  QJQ46_RS11570 (QJQ46_11570) recA 2444608..2445654 (+) 1047 WP_002354860.1 recombinase RecA Machinery gene
  QJQ46_RS11575 (QJQ46_11575) rny 2446051..2447607 (+) 1557 WP_002354863.1 ribonuclease Y -
  QJQ46_RS11580 (QJQ46_11580) - 2447767..2448564 (+) 798 WP_154052235.1 TIGR00282 family metallophosphoesterase -
  QJQ46_RS11585 (QJQ46_11585) - 2448638..2449024 (+) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45167.25 Da        Isoelectric Point: 4.6698

>NTDB_id=828038 QJQ46_RS11565 WP_010706982.1 2443250..2444494(+) (cinA) [Enterococcus faecalis strain HL1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKANEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=828038 QJQ46_RS11565 WP_010706982.1 2443250..2444494(+) (cinA) [Enterococcus faecalis strain HL1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGGCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGGGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB R3KLJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437