Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   QJV49_RS02920 Genome accession   NZ_CP124538
Coordinates   609168..609860 (-) Length   230 a.a.
NCBI ID   WP_225512070.1    Uniprot ID   A0AA49IPC2
Organism   Lactococcus sp. NH2-7C     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 604168..614860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJV49_RS02905 (QJV49_02905) - 605788..606129 (-) 342 WP_225512073.1 P-II family nitrogen regulator -
  QJV49_RS02910 (QJV49_02910) - 606261..607502 (-) 1242 WP_225512072.1 ammonium transporter -
  QJV49_RS02915 (QJV49_02915) covS 607684..609159 (-) 1476 WP_225512071.1 HAMP domain-containing histidine kinase Regulator
  QJV49_RS02920 (QJV49_02920) covR 609168..609860 (-) 693 WP_225512070.1 response regulator transcription factor Regulator
  QJV49_RS02925 (QJV49_02925) - 610016..610546 (-) 531 WP_225512069.1 DUF177 domain-containing protein -
  QJV49_RS02930 (QJV49_02930) - 610677..610922 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  QJV49_RS02935 (QJV49_02935) - 611078..611542 (-) 465 WP_225512068.1 hypothetical protein -
  QJV49_RS02940 (QJV49_02940) - 611624..611986 (-) 363 WP_225512067.1 TIGR02328 family protein -
  QJV49_RS02945 (QJV49_02945) - 612451..613287 (-) 837 WP_255597715.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26698.39 Da        Isoelectric Point: 5.1273

>NTDB_id=826312 QJV49_RS02920 WP_225512070.1 609168..609860(-) (covR) [Lactococcus sp. NH2-7C]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAIERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=826312 QJV49_RS02920 WP_225512070.1 609168..609860(-) (covR) [Lactococcus sp. NH2-7C]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTGGAATTAGAGCATGAAGG
CTATGCGACTGAGATTAAAGATAACGGTCGCTCTGGTCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTCGACGGCTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATTATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGTGCTGATGATTATATCACTAAACCTTTTGCCAT
AGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCACGCCATTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGATAAAACGAATCGTACGGTTCATCGTGGTAAAAAAGTAATTGATTTAACGCGTCGTGAG
TATGACCTTCTTTTGACATTGATGCAAAATGTTGGTGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTAGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAGGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.565

100

0.996
  covR Streptococcus salivarius strain HSISS4

68.103

100

0.687
  vicR Streptococcus mutans UA159

45.887

100

0.461
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.611

98.261

0.37
  ciaR Streptococcus pneumoniae Rx1

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae D39

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae R6

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae TIGR4

36.726

98.261

0.361